Circulating microRNAs in disease diagnostics and their potential biological relevance. (2015)

• Record Type: Book
• Further Information: Note: Peter Igaz, editor.
• Editors: Igaz, Peter
• Contents: Part I: General features and technical issues related to circulating microRNA -- 1. Introduction to microRNAs: biogenesis, action, relevance of tissue microRNAs in disease pathogenesis, diagnosis and therapy. The concept of circulating microRNAs -- 2. Extracellular microRNAs in membrane vesicles and non-vesicular carriers -- 3. Technical aspects related to the analysis of circulating microRNAs -- Part II: Diagnostic relevance of circulating microRNAs -- 4. Circulating blood-borne microRNAs as biomarkers in solid tumors -- 5. Circulating microRNA as biomarkers in hematological malignancies -- 6 Circulating microRNAs as biomarkers in cardiovascular diseases -- 7 Circulating microRNAs in neurodegenerative diseases -- 8 Circulating extracellular microRNA in systemic autoimmunity -- 9. Circulating microRNAs in inflammatory bowel diseases -- 10. Circulating microRNAs in diabetes progression: discovery, validation and research translation -- 11. Diagnostic relevance of microRNAs in other body fluids including urine, feces and saliva -- Part III: Potential biological relevance of circulating microRNA -- 12 Circulating microRNAs as hormones -- intercellular and inter-organ conveyors of epigenetic information? -- 13. Are circulating microRNAs involved in tumor surveillance? -- 14.-Hypothetic interindividual and interspecies relevance of microRNAs released in body fluids.
• Publisher Details: Basel : Springer
• Publication Date: 2015
• Extent: 1 online resource
• Subjects: 572.88; Medicine; Small interfering RNA; Diagnosis; Gene expression; Nucleic acids; Biochemistry; SCIENCE -- Life Sciences -- Biochemistry; Diagnosis; Small interfering RNA; Physiology; Human Anatomy & Physiology; Health & Biological Sciences; Medical -- Biochemistry; Biochemistry; Medical -- Genetics; Medical genetics; RNA, Small Interfering; Biomedicine; Gene Expression; Nucleic Acid Chemistry; Medical Biochemistry; Electronic books; Electronic books
• Languages: English
• ISBNs: 9783034809559; 3034809557
• Related ISBNs: 9783034809535; 3034809530
• Notes: Note: Includes bibliographical references.; Note: Online resource; title from PDF title page (EBSCO, viewed December 11, 2015).
• Access Rights: Legal Deposit; Only available on premises controlled by the deposit library and to one user at any one time; The Legal Deposit Libraries (Non-Print Works) Regulations (UK).
• Access Usage: Restricted: Printing from this resource is governed by The Legal Deposit Libraries (Non-Print Works) Regulations (UK) and UK copyright law currently in force.