Antiepileptic drug discovery : novel approaches /: novel approaches. (2016)

• Record Type: Book
• Further Information: Note: Edited by Alan Talevi, Luisa Rocha.
• Editors: Talevi, Alan; Rocha, Luisa
• Contents: Inflammatory Cytokines as Targets for Epilepsy Drug Therapy -- The Use of Anti-Inflammatory Drugs in Epilepsy -- Carbonic Anhydrase and Epilepsy -- Synaptic Vesicle Protein 2A as a Novel Pharmacological Target with Broad Potential for New Antiepileptic Drugs -- Do Cannabinoids Represent a Good Therapeutic Strategy for Epilepsy? -- Glutamate Receptors as Targets for Novel Antiepileptic Drug Therapy -- Neurosteroid Regulation of Seizures: Role of GABAA Receptor Plasticity -- Erythropoietin as Potential Neuroprotective and Antiepileptogenic Agent in Epilepsy and Refractory Epilepsy -- Caloric Restriction and Dietary Treatments of Epilepsy: Mechanistic Insights for Drug Discovery -- Gene Therapy in Epilepsy -- Human Brain Tissue as a Model for the Study of Epilepsy -- The Blood-Brain Barrier and the Design of New Antiepileptic Drugs -- Virtual Screening Applications in the Search of Novel Antiepileptic Drug Candidates -- Discovering New Antiepileptic Drugs Addressing the Transporter Hypothesis of Refractory Epilepsy: Ligand-Based Approximations -- Discovering New Antiepileptic Drugs Addressing the Transporter Hypothesis of Refractory Epilepsy: Structure-Based Approximations -- Nanoformulations of Antiepileptic Drugs: In Vitro and In Vivo Studies -- Side Effects of Antiepileptic Drugs -- Network Pharmacology and Epilepsy -- The Importance of Drug Repurposing in the Field of Antiepileptic Drug Development.
• Publisher Details: New York, NY : Humana Press
• Publication Date: 2016
• Extent: 1 online resource (xi, 386 pages), illustrations (some color)
• Subjects: 615.7/84; Medicine; Anticonvulsants -- Laboratory manuals; Drug development -- Laboratory manuals; Anticonvulsants; Drug development; Anticonvulsants -- pharmacology; Epilepsy -- drug therapy; Drug Discovery -- methods; Toxicology; Medical -- Pharmacology; Pharmacology; Electronic books; Laboratory manuals
• Languages: English
• ISBNs: 9781493963553; 1493963554
• Related ISBNs: 9781493963539; 1493963538
• Notes: Note: Includes bibliographical references and index.; Note: Online resource; title from PDF title page (SpringerLink, viewed September 30, 2016).
• Access Rights: Legal Deposit; Only available on premises controlled by the deposit library and to one user at any one time; The Legal Deposit Libraries (Non-Print Works) Regulations (UK).
• Access Usage: Restricted: Printing from this resource is governed by The Legal Deposit Libraries (Non-Print Works) Regulations (UK) and UK copyright law currently in force.