Genome editing : the next step in gene therapy /: the next step in gene therapy. (2016)

• Record Type: Book
• Further Information: Note: Toni Cathomen, Matthew Hirsch, Matthew Porteus, editors.
• Editors: Cathomen, Toni; Hirsch, Matthew; Porteus, Matthew H
• Contents: 1. Gene Editing: Double-Strand Break Induced Gene Targeting and Mutagenesis 20 Years Later -- 2. The Development and Use of Zinc-Finger Nucleases -- 3. The Use and Development of TAL Effector Nucleases -- 4. Genome Editing for Neuromuscular Diseases -- 5. Phage Integrases for Genome Editing -- 6. Precise Genome Modification Using Triplex Forming Oligonucleotides and Peptide Nucleic Acids -- 7. Genome Editing by Aptamer-Guided Gene Targeting -- 8. Stimulation of AAV Gene Editing via DSB Repair -- 9. Engineered Nucleases and Trinucleotide Repeat Diseases -- 10. Using Engineered Nucleases to Create HIV-Resistant Cells -- 11. Strategies to Determine Off-Target Effects of Engineered Nucleases.
• Publisher Details: New York, NY : Springer
• Publication Date: 2016
• Extent: 1 online resource (xvi, 263 pages), illustrations (some color)
• Subjects: 660.6/5; Medicine; Genetic engineering; Gene therapy; SCIENCE -- Chemistry -- Industrial & Technical; TECHNOLOGY & ENGINEERING -- Chemical & Biochemical; Gene therapy; Genetic engineering; Bioengineering; Genetic Therapy; Biomedicine; Human Genetics; Human genetics; Medical -- Genetics; Medical genetics; Electronic books
• Languages: English
• ISBNs: 9781493935093; 1493935097; 1493935070; 9781493935079
• Related ISBNs: 9781493935079
• Notes: Note: Online resource; title from PDF title page (SpringerLink, viewed March 7, 2016).
• Access Rights: Legal Deposit; Only available on premises controlled by the deposit library and to one user at any one time; The Legal Deposit Libraries (Non-Print Works) Regulations (UK).
• Access Usage: Restricted: Printing from this resource is governed by The Legal Deposit Libraries (Non-Print Works) Regulations (UK) and UK copyright law currently in force.