Circulating tumor cells. (2016)

• Record Type: Book
• Further Information: Note: Richard J. Cote, Ram H. Datar, editors.
• Editors: Cote, Richard J; Datar, Ram
• Contents: Preface -- Foreword -- Section I. Technologies for CTC Identification -- 1. Significance of Studying Circulating Tumor Cells -- 2. Affinity-Based Enrichment of Circulating Tumor Cells -- 3. Size-Based and Non-Affinity Based Microfluidic Devices for Circulating Tumor Cell Enrichment and Characterization -- 4. Molecular Assays for the Detection and Molecular Characterization of CTCs -- 5. Cancer Stem Cells and Circulating Tumor Cells Molecular Markers, Isolation Techniques and Clinical Implications -- Section II. Fundamental Studies of CTC -- 6. Circulating Tumor Cells and Tumor Dormancy.- 7. Prevention of Conversion of Tumor Dormancy into Proliferative Metastases -- 8. Genesis of Circulating Tumor Cells through Epithelial-Mesenchymal Transition as a Mechanism for Distant Dissemination -- Section III. CTC Analysis -- 9. CTC Analysis FISH, ISH, Array-CGH and Other Molecular Assays -- 10. Genome-Wide Gene Copy Number Analysis of Circulating Tumor Cells -- 11. Perspectives on the Functional Characterization and In Vitro Maintenance of Circulating Tumor Cells -- 12. Prognostic Implications of CTC in Breast Cancer -- Section IV. Potential Clinical Applications of CTC -- 13. CTC in Advanced Breast Cancer Prognosis, Monitoring and Clinical Utility -- 14. Evolution of Metastatic Disease: The Need for Monitoring and Emerging Therapeutic Opportunities -- 15. CTC for Biomarker and Companion Diagnostic Development -- 16. Perspectives on Clinical Applications of CTCs -- Index.
• Publisher Details: New York, NY : Springer
• Publication Date: 2016
• Extent: 1 online resource (xxiv, 333 pages), illustrations (some color)
• Subjects: 616.99/407; Medicine; Metastasis; Cancer invasiveness; HEALTH & FITNESS -- Diseases -- General; MEDICAL -- Clinical Medicine; MEDICAL -- Diseases; MEDICAL -- Evidence-Based Medicine; MEDICAL -- Internal Medicine; Cancer invasiveness; Metastasis; Biomedicine; Cancer Research; Oncology; Medical -- Oncology; Oncology; Electronic books
• Languages: English
• ISBNs: 9781493933631; 1493933639
• Related ISBNs: 9781493933617; 1493933612
• Notes: Note: Includes bibliographical references and index.; Note: Online resource; title from PDF title page (SpringerLink, viewed February 16, 2016).
• Access Rights: Legal Deposit; Only available on premises controlled by the deposit library and to one user at any one time; The Legal Deposit Libraries (Non-Print Works) Regulations (UK).
• Access Usage: Restricted: Printing from this resource is governed by The Legal Deposit Libraries (Non-Print Works) Regulations (UK) and UK copyright law currently in force.