Assessing rare variation in complex traits : design and analysis of genetic studies /: design and analysis of genetic studies. (2015)

• Record Type: Book
• Further Information: Note: Eleftheria Zeggini, Andrew Morris, editors.
• Editors: Zeggini, Eleftheria; Morris, Andrew Paul
• Contents: Calling Rare Variants from Genotype Data -- Calling Variants from Sequence Data -- Rare Variant Quality Control -- Rare Structural Variants -- Functional Annotation of Rare Genetic Variants -- The 1000 Genomes Project -- The UK10K Project -- Population Isolates -- Natural Selection at Rare Variants -- Collapsing Approaches for the Association Analysis of Rare Variants -- Rare Variant Association Analysis: Beyond Collapsing Approaches -- Significance Thresholds for Rare Variant Signals -- Power of Rare Variant Aggregate Tests -- Replicating Sequence-based Association Studies of Rare Variants -- Meta-analysis of Rare Variants -- Population Stratification of Rare Variants -- Use of Appropriate Controls in Rare Variant Studies -- Trans-ethnic Fine-mapping of Rare Causal Variants.
• Publisher Details: New York : Springer
• Publication Date: 2015
• Extent: 1 online resource (xi, 261 pages), illustrations
• Subjects: 599.9/4; Medicine; Human genetics -- Variation; Genomics; NATURE -- Animals -- Mammals; SCIENCE -- Life Sciences -- Zoology -- Mammals; Genomics; Human genetics -- Variation; Genetic Variation; Genomics; Biomedicine; Human Genetics; Molecular Medicine; Statistics for Life Sciences, Medicine, Health Sciences; Science -- Life Sciences -- Biology -- Molecular Biology; Medical -- Biostatistics; Medical research; Probability & statistics; Human genetics; Statistics; Medical -- Genetics; Medical genetics; Electronic books
• Languages: English
• ISBNs: 9781493928248; 1493928244; 1493928236; 9781493928231
• Related ISBNs: 9781493928231
• Notes: Note: Includes bibliographical references.; Note: Online resource; title from PDF title page (SpringerLink, viewed August 18, 2015).
• Access Rights: Legal Deposit; Only available on premises controlled by the deposit library and to one user at any one time; The Legal Deposit Libraries (Non-Print Works) Regulations (UK).
• Access Usage: Restricted: Printing from this resource is governed by The Legal Deposit Libraries (Non-Print Works) Regulations (UK) and UK copyright law currently in force.