Innovations for next-generation antibody-drug conjugates. (2018)

• Record Type: Book
• Further Information: Note: Edited by Marc Damelin.
• Editors: Damelin, Marc
• Contents: Chapter 1 Introduction: Motivations for Next-Generation ADCs -- Chapter 2 Combining ADCs with Immuno-oncology Agents -- Chapter 3 Improving the Safety Profile of ADCs -- Chapter 4 Utility of PK-PD Modeling and Simulation to Improve Decision Making for Antibody-Drug Conjugate Development -- Chapter 5 Regulatory Considerations and Companion Diagnostics -- Chapter 6 ADC Process Development and Manufacturing -- Chapter 7 HER2-Targeted ADCs: At the forefront of ADC technology development -- Chapter 8 Next generation payloads for ADCs -- Chapter 9 Delivering more payload: High DAR ADCs -- Chapter 10 Site-Specific Antibody Drug Conjugates -- Chapter 11 Bispecific and Biparatopic Antibody-Drug Conjugates -- Chapter 12 drug conjugates to the tumor microenvironment: Probody Drug Conjugates -- Chapter 13 Antibody-Drug Conjugates: Targeting the Tumor Microenvironment -- Chapter 14 Next Horizons: ADCs Beyond Oncology.
• Publisher Details: Cham : Springer International Publishing Imprint Humana Press
• Publication Date: 2018
• Extent: 1 online resource
• Subjects: 615.3/7; Antibody-drug conjugates -- Technological innovations; Cancer -- Research; Molecular biology; MEDICAL -- Pharmacology; Cancer -- Research; Medicine; Molecular biology; Electronic books
• Languages: English
• ISBNs: 9783319781549; 3319781545
• Related ISBNs: 3319781537; 9783319781532
• Access Rights: Legal Deposit; Only available on premises controlled by the deposit library and to one user at any one time; The Legal Deposit Libraries (Non-Print Works) Regulations (UK).
• Access Usage: Restricted: Printing from this resource is governed by The Legal Deposit Libraries (Non-Print Works) Regulations (UK) and UK copyright law currently in force.