Extraskeletal effects of Vitamin D : a clinical guide /: a clinical guide. (2018)

• Record Type: Book
• Further Information: Note: Emilia Pauline Liao, editor.
• Editors: Liao, Emilia Pauline
• Contents: Intro; Series Editor Foreword; Preface; Contents; Contributors; Chapter 1: Vitamin D Biochemistry and Physiology; Introduction; Vitamin D Production; Vitamin D Metabolism; Transport of Vitamin D Metabolites in the Blood and Their Cellular Uptake; Vitamin D Mechanism of Action; Vitamin D Regulation of Cellular Function; Classic Vitamin D Target Tissues; Nonclassic Vitamin D Target Tissues; Regulation of Proliferation and Differentiation; Regulation of Hormone Secretion; Regulation of the Immune System; References; Chapter 2: Vitamin D and Autoimmune Diseases; Introduction; Vitamin D Deficiency Systemic Lupus ErythematosusType 1 Diabetes Mellitus; Multiple Sclerosis; Inflammatory Bowel Diseases; Rheumatoid Arthritis; Psoriasis; Other Autoimmune Diseases; Possible Underlying Mechanism; Conclusion; References; Chapter 3: Vitamin D and Infectious Diseases; Why Would Vitamin D Have an Impact on Infectious Diseases?; Historical Aspects; Cod Liver Oil; Light on Mycobacteria; Vitamin D Used in Treatment; Infections Where VD Has Been Hypothesized to Play a Role; Tuberculosis; TB Immunopathology in Relation to Vitamin D-Mediated Immunology Epidemiological Aspects: Vitamin D Status Among Patients with Active TB InfectionGenetic Aspects: Vitamin D Receptor and Susceptibility Toward TB; Intervention Studies Supplementing Patients with TB with Vitamin D; Other Respiratory Tract Infections; Intervention Studies on Respiratory Tract Infections; Methicillin-Resistant Staphylococcus aureus (MRSA) Carriage in Airways; Sepsis; Observational Studies on Vitamin D and Sepsis; Vitamin D Supplementation Trials; Human Immunodeficiency Virus; Association of Anti-retroviral Treatment (ART) and Vitamin D; Vitamin D Supplementation to HIV Infected Hepatitis C VirusAssociation of Vitamin D Deficiency with Disease Severity and Sustained Viral Response; Vitamin D Supplementation and Hepatitis; Hepatitis C and HIV Coinfection; Vitamin D as Risk Marker for Infection and Role in Antimicrobial Treatment and Prevention; References; Chapter 4: Vitamin D Hormone Action in the Endocrine Tissue: Implications for Prostate and Breast Carcinoma; Introduction; Vitamin D Metabolism; Synthesis, Degradation, and Roles and Regulation of Key Enzymes; Vitamin D Metabolism in the Prostate Transcription Regulation by VDR: Domain Structure and Roles for Ligands, DNA Response Elements, and CoregulatorsFunctional Domains of VDR and Inter-domain Allostery; Naturally Occurring VDR Ligands; Calcitriol, Calcidiol, and Secondary Bile Acids; Agonist Actions of Calcitriol and Calcidiol on VDR: Analysis by Molecular Docking; Gene Regulation by VDR: Roles for Coregulators and DNA Response Elements; Interplay of Androgen and Vitamin D in Prostate: Impacts on Cell Proliferation, Vitamin D Metabolism, and the AR Pathway; Effects on Cell Cycle Regulation and E2F1, a Key Cell Cycle Regulator
• Publisher Details: Cham, Switzerland : Humana Press
• Publication Date: 2018
• Extent: 1 online resource
• Subjects: 612.3/99; Medicine; Vitamin D; Vitamin D in the body; MEDICAL / Physiology; SCIENCE / Life Sciences / Human Anatomy & Physiology; Vitamin D; Vitamin D in the body; Medical -- Nutrition; Dietetics & nutrition; Endocrinology; Personal health and hygiene; Medical -- Endocrinology & Metabolism; Endocrinology; Electronic books
• Languages: English
• ISBNs: 9783319737423; 3319737422
• Related ISBNs: 9783319737416
• Notes: Note: Online resource; title from PDF title page (SpringerLink, viewed May 2, 2018).
• Access Rights: Legal Deposit; Only available on premises controlled by the deposit library and to one user at any one time; The Legal Deposit Libraries (Non-Print Works) Regulations (UK).
• Access Usage: Restricted: Printing from this resource is governed by The Legal Deposit Libraries (Non-Print Works) Regulations (UK) and UK copyright law currently in force.