Resistance to anti-cancer therapeutics targeting receptor tyrosine kinases and downstream pathways. (2018)

• Record Type: Book
• Further Information: Note: Yosef Yarden, Moshe Elkabets, editors.
• Editors: Yarden, Y (Yosef); Elkabets, Moshe
• Contents: Resistance of colorectal tumors to anti-EGFR antibodies -- Resistance of lung cancer to kinase inhibitors specific to EGFR or ALK -- Mechanisms of action and resistance of trastuzumab in breast cancer -- Mechanisms of resistance to molecular therapies targeting the HGF/MET axis -- RAF, MEK and ERK inhibitors as anti-cancer drugs: intrinsic and acquired resistance as a major therapeutic challenge -- Mechanisms of resistance to PI3K and AKT inhibitors -- Sensitivity and resistance to BH3 mimetics in cancer therapy -- Resistance mechanisms to cyclin-dependent kinase inhibitors -- Resistance to inhibitors of angiogenesis.
• Publisher Details: Cham, Switzerland : Springer
• Publication Date: 2018
• Extent: 1 online resource
• Subjects: 616.99/4061; Medicine; Drug resistance in cancer cells; Antineoplastic agents; Cancer -- Chemotherapy; HEALTH & FITNESS -- Diseases -- General; MEDICAL -- Clinical Medicine; MEDICAL -- Diseases; MEDICAL -- Evidence-Based Medicine; MEDICAL -- Internal Medicine; Antineoplastic agents; Cancer -- Chemotherapy; Drug resistance in cancer cells; Oncology; Medical -- Oncology; Oncology; Electronic books
• Languages: English
• ISBNs: 9783319679327; 3319679325
• Related ISBNs: 9783319679303; 3319679309
• Notes: Note: Includes bibliographical references and index.; Note: Online resource; title from PDF title page (SpringerLink, viewed April 5, 2018).
• Access Rights: Legal Deposit; Only available on premises controlled by the deposit library and to one user at any one time; The Legal Deposit Libraries (Non-Print Works) Regulations (UK).
• Access Usage: Restricted: Printing from this resource is governed by The Legal Deposit Libraries (Non-Print Works) Regulations (UK) and UK copyright law currently in force.