Cartilage. Repair strategies and regeneration / Volume 3, (2017)

• Record Type: Book
• Other Titles: Repair strategies and regeneration
• Further Information: Note: Susanne Grässel, Attila Aszódi, editors.
• Editors: Grässel, Susanne; Aszódi, Attila
• Contents: Preface; Contents; List of Contributors; 1: Overview: State of the Art and Future Prospectives for Cartilage Repair; 1.1 Introduction; 1.1.1 Clinical Relevance and Needs of Cartilage Repair; 1.2 Cartilage Structure, Function, and Injuries; 1.2.1 Cartilage Structure; 1.2.2 Cartilage Injury; 1.2.3 Clinical Outcomes of Treatments; 1.3 Current Cartilage Repair Strategies; 1.3.1 Palliative Approach: Arthroscopic Debridement/Lavage; 1.3.2 Intrinsic Repair: Bone Marrow Stimulation Technique-Abrasion, Drilling, and Microfracture. 1.3.3 Whole Tissue Transplantation: Osteochondral Graft Transplantation1.3.4 Tissue-Engineered Cartilage; 1.3.4.1 Autologous Chondrocyte Implantation/Transplantation (ACI/ ACT); 1.3.5 Total Joint Replacement; 1.4 New Strategies Under Investigation; 1.4.1 Cell-Based Therapies; 1.4.1.1 Stem Cells; Stem Cell Types Relevant to Cartilage Repair; Signaling Factors: Stem Cell Differentiation and Cell Phenotype Maintenance; 1.4.1.2 Allogeneic Chondrocytes; 1.4.2 Biomaterial Scaffolds for Cartilage Repair; 1.4.2.1 Current Biomaterials and 3D Scaffolds. 1.4.2.2 Major Concerns in Scaffold Design1.5 Unsolved Problems and Challenges in Cartilage Repair; 1.5.1 Tissue Integration; 1.5.2 Maintenance of Cell Phenotype; 1.5.3 Simplifying Surgical and Rehabilitation Procedures; 1.5.4 Prevention of OA Progress; 1.5.4.1 Establishing Correct Joint Mechanical Environment; 1.5.4.2 Rebuilding Subchondral Bone; 1.5.4.3 Anti-Inflammatory Actions; References; 2: MSC Populations for Cartilage Regeneration; 2.1 Embryonic Origin of Chondroprogenitor Cells (CPCs); 2.2 In Vivo Presence of MSCs in Adult Joints; 2.2.1 Characteristics of MSCs In Vivo. 2.2.1.1 Articular Cartilage-Derived Chondroprogenitor cells (CPCs)2.2.1.2 Bone Marrow-Derived MSCs (BMSCs); 2.2.1.3 Synovium-Derived MSCs (SM-MSCs); 2.2.1.4 Synovial Fluid-Derived MSCs (SF-MSCs); 2.2.1.5 Infrapatellar Fat Pad-Derived MSCs (IF-MSCs); 2.2.2 Contribution to Repair by MSCs In Vivo; 2.3 MSCs In Vitro; 2.3.1 Articular Cartilage-Derived MSCs (AC-MSCs); 2.3.2 Bone Marrow-Derived MSCs (BMSCs); 2.3.3 Synovium-Derived MSCs (SM-MSCs); 2.3.4 Synovial Fluid-Derived MSCs (SF-MSCs); 2.3.5 Infrapatellar Fat Pad-Derived MSCs (IF-MSCs). 2.4 Manipulation of Joint Stem Cell Phenotype In Vitro by Growth FactorsReferences; 3: Chondrogenic Progenitor Cells and Cartilage Repair; 3.1 Osteoarthritis and Rheumatoid Arthritis; 3.2 Regeneration Attempts in Cartilage Tissue; 3.2.1 Mesenchymal Stem Cells and Osteoarthritis; 3.2.2 Mesenchymal Stem Cells and Rheumatoid Arthritis; 3.3 Chondrogenic Progenitor Cells; 3.3.1 Chondrogenic Progenitor Cells from Osteoarthritic Patients (CPCs); 3.3.2 Chondrogenic Progenitor Cells from Rheumatoid Arthritis Patients; 3.3.3 Meniscus Progenitor Cells (MPCs); References.
• Publisher Details: Cham, Switzerland : Springer
• Publication Date: 2017
• Extent: 1 online resource
• Subjects: 612.7/517; 610; Medicine; Cartilage; Cartilage -- Regeneration; HEALTH & FITNESS -- Holism; HEALTH & FITNESS -- Reference; MEDICAL -- Alternative Medicine; MEDICAL -- Atlases; MEDICAL -- Essays; MEDICAL -- Family & General Practice; MEDICAL -- Holistic Medicine; MEDICAL -- Osteopathy; Cartilage; Cartilage -- Regeneration; Cartilage; Biomedicine; Human Physiology; Orthopedics; Regenerative Medicine/Tissue Engineering; Stem Cells; Medical -- Orthopedics; Science -- Life Sciences -- Biology -- Molecular Biology; Science -- Life Sciences -- Cytology; Orthopaedics & fractures; Cellular biology (cytology); Genetics (non-medical); Human physiology; Orthopedics; Stem cells; Medical -- Physiology; Physiology; Electronic books; Electronic book
• Languages: English
• ISBNs: 9783319533162; 3319533169
• Related ISBNs: 9783319533148; 3319533142
• Notes: Note: Includes bibliographical references at the end of each chapters.; Note: Online resource; title from PDF title page (SpringerLink, viewed May 24, 2017).
• Access Rights: Legal Deposit; Only available on premises controlled by the deposit library and to one user at any one time; The Legal Deposit Libraries (Non-Print Works) Regulations (UK).
• Access Usage: Restricted: Printing from this resource is governed by The Legal Deposit Libraries (Non-Print Works) Regulations (UK) and UK copyright law currently in force.