Stem cells and cardiac regeneration. (©2016)

• Record Type: Book
• Further Information: Note: Rosalinda Madonna, editor.
• Other Names: Madonna, Rosalinda
• Contents: Dedication; Preface; About the Author; Acknowledgments; Abbreviations; Contents; Contributors; Part I: Stem Cells Sources for Cardiac Regeneration. Basic Principles; Chapter 1: Biology and Function of Stem Cells; 1.1 Basics of Stem Cell Biology; 1.2 Pluripotent Versus Multipotent Stem Cells; 1.3 Basic Requirements of Stem Cell Sources for Cardiac Regeneration; 1.4 Adult Stem Cell Plasticity; References; Chapter 2: Embryonic Stem Cells for Cardiac Regeneration; 2.1 Introduction; 2.2 Murine Embryonic Stem Cells Isolation, Characterization and CM Differentiation. 2.3 Human Embryonic Stem Cells Isolation, Characterization and CM Differentiation2.4 Advantages and Disadvantages of Embryonic Stem Cells as Source for Cardiac Regeneration; 2.5 Future Trends in the Therapeutic Application of hESCs for Cardiac Regeneration; References; Chapter 3: Induced Pluripotent Stem Cells for Cardiac Regeneration; 3.1 Human Induced Pluripotent Stem Cells; 3.2 Methods to Develop Human Induced Pluripotent Stem Cells; 3.3 Genome Editing and Human Induced Pluripotent Stem Cells; 3.4 Human Induced Pluripotent Stem Cells as Model of Human Disease; References. Chapter 4: Tissue Specific Progenitors/Stem Cells for Cardiac Regeneration4.1 Bone Marrow-Derived Stem Cells; 4.2 Endothelial Progenitor Cells; 4.3 Adipose Tissue-Derived Stem Cells; 4.4 Cardiac Stem Cells; References; Part II: Critical Regulators of Stem Cell Differentiation for Myocardial Regeneration; Chapter 5: Circadian Rhythms in Stem Cell Biology and Function; 5.1 Introduction; 5.2 The Core Clock Machinery; 5.2.1 A Complex Transcriptional Feedback Loop Defines the Molecular Clock; 5.2.2 Epigenetic Regulation of the Circadian Clock. 5.2.3 Additional Regulatory Systems Fine-Tune Circadian Rhythmicity5.3 Circadian Rhythms in Tissue/Organ Physiology; 5.3.1 Tissue Specific Control of Clock Output; 5.3.2 Transgenic Animals Provide Novel Insights to Better Understand the Clock; 5.3.3 Circadian Rhythms in the Heart; 5.4 Ontology of Circadian Rhythms and the Role of Clocks in Cell Cycle; 5.4.1 Circadian Clocks During Embryonic Development; 5.4.2 Oscillation of Core Clock Genes upon Differentiation of Embryonic Stem Cells; 5.4.3 Role of the Circadian Clock in Cell Cycle; 5.5 Circadian Rhythms in Adult Stem Cells. 5.5.1 Regulation of Adult Stem Cells by Oscillatory Systems5.5.2 Circadian Clock Gene Expression in Adult Stem Cells; 5.6 The Role of Circadian Rhythms in Tissue Regeneration for Cell-Based Therapy; References; Chapter 6: Cardiac Regeneration and microRNAs: Regulators of Pluripotency, Reprogramming, and Cardiovascular Lineage Commitment; 6.1 The Cellular Function of microRNAs; 6.1.1 Introduction; 6.1.2 Biogenesis of microRNAs; 6.1.3 microRNA Target Recognition; 6.1.4 microRNA-Induced Silencing Complex; 6.2 The Role of microRNAs in Pluripotent Stem Cells; 6.2.1 Introduction.
• Publisher Details: Cham : Springer
• Publication Date: 2016
• Copyright Date: 2016
• Extent: 1 online resource
• Subjects: 612.1/7045; 570; Life sciences; Myocardium -- Regeneration; Stem cells; Heart cells; MEDICAL -- Physiology; SCIENCE -- Life Sciences -- Human Anatomy & Physiology; Heart cells; Myocardium -- Regeneration; Stem cells; Myocardium; Regeneration; Stem Cells; Science -- Life Sciences -- Biology -- Molecular Biology; Medical -- Cardiology; Cellular biology (cytology); Cardiovascular medicine; Cardiology; Science -- Life Sciences -- Cytology; Genetics (non-medical); Electronic books
• Languages: English
• ISBNs: 9783319254272; 3319254278; 3319254251; 9783319254258
• Related ISBNs: 9783319254258; 3319254251
• Notes: Note: Includes bibliographical references and index.; Note: Print version record.
• Access Rights: Legal Deposit; Only available on premises controlled by the deposit library and to one user at any one time; The Legal Deposit Libraries (Non-Print Works) Regulations (UK).
• Access Usage: Restricted: Printing from this resource is governed by The Legal Deposit Libraries (Non-Print Works) Regulations (UK) and UK copyright law currently in force.