G protein-coupled receptor kinases. (2016)

• Record Type: Book
• Further Information: Note: Edited by Vsevolod V. Gurevich, Eugenia V. Gurevich, John J.G. Tesmer.
• Editors: Gurevich, Vsevolod V; Gurevich, Eugenia V; Tesmer, John J. G
• Contents: Part I: Introduction 1. G Protein-Coupled Receptor Kinases (GRKs) History: Evolution and Discovery Vsevolod V. Gurevich and Eugenia V. Gurevich Part II: GRK Structure, Mechanisms of Activation, and Interaction with GPCRs 2. Structure and Function of G Protein-Coupled Receptor Kinases 1 and 7 Tivadar Orban and Krzysztof Palczewski 3. Visual G Protein-Coupled Receptor KinasesChih-Chun Hsu and Ching-Kang Jason Chen 4. Molecular Basis for Targeting, Inhibition, and Receptor Phosphorylation in the G Protein-Coupled Receptor Kinase 4 Subfamily Tyler S. Beyett, Sumit J. Bandekar, and John J.G. Tesmer 5. 'Barcode' and Differential Effects of GPCR Phosphorylation by Different GRKs Kunhong Xiao and Hongda Liu Part III: GRKs in Cell Signaling 6. Cell-Type Specific GRK2 Interactomes: Physiopathological Implications Federico Mayor, Jr., Rocío Vila-Bedmar, Laura Nogués, Marta Cruces-Sande, Elisa Lucas, Verónica Rivas, Clara Reglero, Petronila Penela, and Cristina Murga 7. Differential Regulation of IGF-1 and Insulin Signaling by GRKs Leonard Girnita, Ada Girnita, and Caitrin Crudden 8. Differential Control of Potassium Channel Activity by GRK2Adi Raveh, Liora Guy-David, and Eitan Reuveny Part IV: Physiological and Pathophysiological Mechanisms Regulated by GRKs 9. Critical Role of GRK2 in the Prevention of Chronic Pain Faiza Baameur, Pooja Singhmar, Cobi J. Heijnen, and Annemieke Kavelaars 10. Roles of GRK Dysfunction in Alzheimer's Pathogenesis William Z. Suo 11. Regulation of Dopamine-Dependent Behaviors by G Protein-Coupled Receptor KinasesEugenia V. Gurevich, Raul R. Gainetdinov, and Vsevolod V. Gurevich 12. G Protein-Coupled Receptors and Their Kinases in Cardiac Regulation Alessandro Cannavo, Claudio de Lucia, and Walter J. Koch 13. GRK Roles in C. elegans Jordan F. Wood and Denise M. Ferkey 14. Evolutionarily Conserved Role of G Protein-Coupled Receptor Kinases in the Hedgehog Signaling Pathway Dominic Maier and David R. Hipfner.
• Publisher Details: New York, NY : Humana Press
• Publication Date: 2016
• Extent: 1 online resource (xi, 329 pages), illustrations (some color)
• Subjects: 572/.696; Medicine; G proteins -- Laboratory manuals; Protein kinases -- Laboratory manuals; G proteins; Protein kinases; G-Protein-Coupled Receptor Kinases; Toxicology; Medical -- Pharmacology; Pharmacology; Electronic books; Laboratory manuals; Laboratory Manuals
• Languages: English
• ISBNs: 9781493937981; 1493937987; 1493937960; 9781493937967
• Related ISBNs: 9781493937967
• Notes: Note: Includes bibliographical references and index.; Note: Online resource; title from PDF title page (SpringerLink, viewed July 28, 2016).
• Access Rights: Legal Deposit; Only available on premises controlled by the deposit library and to one user at any one time; The Legal Deposit Libraries (Non-Print Works) Regulations (UK).
• Access Usage: Restricted: Printing from this resource is governed by The Legal Deposit Libraries (Non-Print Works) Regulations (UK) and UK copyright law currently in force.