Parental obesity : intergenerational programming and consequences /: intergenerational programming and consequences. (2016)

• Record Type: Book
• Further Information: Note: Lucy R. Green, Robert L. Hester, editors.
• Other Names: Green, Lucy R; Hester, Robert L
• Contents: Preface; References; Acknowledgments; Contents; Chapter 1: Why Obesity in Parents Matters; 1.1 The Challenge; 1.2 New Insights into the Importance of Healthy Early Development; 1.3 Obesity in Adolescents and Young People; 1.4 Meeting the Challenge; 1.5 Conclusion; References; Chapter 2: Maternal Obesity During Pregnancy and Cardiometabolic Development in the Offspring; 2.1 Introduction; 2.2 The Generation R Study; 2.3 Maternal Prepregnancy Body Mass Index; 2.4 Maternal Gestational Weight Gain; 2.5 Causality of the Observed Associations; 2.5.1 Sibling Comparison Studies. 2.5.2 Parent-Offspring Comparison Studies2.5.3 Mendelian Randomization Studies; 2.5.4 Randomized Controlled Trials; 2.6 Underlying Mechanisms; 2.6.1 Maternal Exposures; 2.6.2 Programming Mechanisms; 2.7 Challenges for Future Epidemiological Research; 2.8 Conclusions; References; Chapter 3: Maternal Obesity and Gestational Weight Gain as Determinants of Long-Term Health; 3.1 The Global Prevalence of Maternal Obesity; 3.2 Implications of Maternal Obesity on Conception and Pregnancy Outcomes; 3.2.1 Preconception and Embryogenesis; 3.2.2 The Antenatal Period; 3.2.3 Gestational Weight Gain. 3.2.3.1 What Is Gestational Weight Gain?3.2.3.2 Excessive Gestational Weight Gain; 3.2.3.3 Below Recommended Gestational Weight Gain; 3.2.3.4 Assessment of Gestational Weight Gain; 3.3 Effect of Maternal Obesity and Gestational Weight Gain on Long-Term Health of the Child; 3.3.1 Developmental Programming Hypothesis; 3.3.2 The Influence of the In Utero Environment on Offspring Outcomes; 3.3.3 Pre-pregnancy Obesity; 3.3.4 Gestational Weight Gain; 3.4 Drawbacks of Birth CohortsIn Interpreting Matenal/Offspring Associations. 3.5 Dietary Determinants of Associations Between Maternal Exposures and Offspring Outcomes3.6 Summary; 3.7 Putative Mechanisms Relating Maternal Obesity to Offspring Outcomes; 3.7.1 Maternal Obesity, Oocyte Quality and Embryogenesis; 3.7.2 Metabolic Stress and the HPA Axis; 3.7.3 Adipokines; 3.7.4 The Metabolome; 3.8 Role of Interventions Studies; 3.9 Conclusion; References; Chapter 4: Young Maternal Age, Body Composition and Gestational Intake Impact Pregnancy Outcome: Translational Perspectives; 4.1 Introduction; 4.2 Adverse Pregnancy Outcome: Who Is at Risk? 4.2.1 Maternal Body Composition at Conception4.2.2 Young Maternal Age; 4.3 Nutrition, Growth and Pregnancy Outcome in Young Adolescent Sheep; 4.3.1 Basic Adolescent Sheep Paradigm; 4.3.2 Pregnancy Outcome in Overnourished Adolescents; 4.3.3 Pregnancy Outcome in Undernourished Adolescents; 4.3.4 BMI at Conception Versus Gestational Intake; 4.3.5 Donor Ewe Adiposity Versus BMI at Conception; 4.3.6 Maternal Adaptations to Diverse Gestational Intakes; 4.3.7 Placental Adaptations to Diverse Gestational Intakes; 4.3.8 Fetal Consequences of Diverse Gestational Intakes.
• Publisher Details: New York, NY, UNITED STATES : Springer
• Publication Date: 2016
• Extent: 1 online resource (396)
• Subjects: 616.3/98; 610; Medicine; Obesity; Obesity in women; HEALTH & FITNESS -- Diseases -- General; MEDICAL -- Clinical Medicine; MEDICAL -- Diseases; MEDICAL -- Evidence-Based Medicine; MEDICAL -- Internal Medicine; Obesity; Obesity in women; Science -- Life Sciences -- Zoology -- General; Medical -- Genetics; Medical -- Nursing -- Maternity, Perinatal, Women's Health; Medical -- Preventive Medicine; Animal physiology; Medical genetics; Materno-fetal medicine; Public health & preventive medicine; Human physiology; Animal physiology; Gene expression; Maternal and infant welfare; Medical -- Physiology; Physiology; Electronic books
• Languages: English
• ISBNs: 9781493963867; 1493963864
• Related ISBNs: 9781493963843; 1493963848
• Notes: Note: Includes bibliographical references.; Note: Print version record.
• Access Rights: Legal Deposit; Only available on premises controlled by the deposit library and to one user at any one time; The Legal Deposit Libraries (Non-Print Works) Regulations (UK).
• Access Usage: Restricted: Printing from this resource is governed by The Legal Deposit Libraries (Non-Print Works) Regulations (UK) and UK copyright law currently in force.