Treatment of chronic pain by medical approaches : the American Academy of Pain Medicine textbook on patient management /: the American Academy of Pain Medicine textbook on patient management. ([2015])

• Record Type: Book
• Other Titles: Treatment of Chronic Pain by Medical Approaches
• Further Information: Note: Timothy R. Deer, editor-in-chief, Michael S. Leong, associate editor-in-chief ; Vitaly Gordin, associate editor.
• Editors: Deer, Timothy R; Leong, Michael S; Gordin, Vitaly
• Other Names: Deer, Timothy R; American Academy of Pain Medicine, issuing body.
• Contents: Foreword to Comprehensive Treatmentof Chronic Pain by Medical, Interventional, and Integrative Approaches; Foreword to Comprehensive Treatmentof Chronic Pain by Medical, Interventional, and Integrative Approaches; Preface to Treatment of Chronic Pain by Medical Approaches; Preface to Comprehensive Treatment of Chronic Pain by Medical, Interventional, and Integrative Approaches; Contents; Contributors; 1: A Survey of Systems Involved in Nociceptive Processing; Key Points; Background; Overview of the Psychophysics of Nociception; Acute Stimulation; Tissue Injury; Nerve Injury. Encoding of Acute NociceptionTransduction Channels and Afferent Terminal Activation; Chemical Sensitivity of Temperature Channels; Action Potential Generation; Encoding Properties of Primary Afferents; Afferent Synaptic Transmission; Calcium Channels and Afferent Transmitter Release; Spinal Afferent Terminal Transmitters; Laminar Organization of Spinal Dorsal Horn; Primary Afferent Projections; Dorsal Horn Neurons; Dorsal Horn Projections; Supraspinal Organization; Encoding of Nociception After Tissue Injury; Peripheral Changes in Afferent Transmission Resulting from Tissue. Origin of Ongoing Activity and Enhanced Terminal Responsiveness After Tissue Injury Spinal Changes in Afferent Transmission Resulting from Tissue Injury; Central (Spinal) Facilitation; Enhanced Response of WDR Neuron; Pharmacology of Central Facilitation; Primary Afferents; Postsynaptic to the Primary Afferents; Local Interneuronal Networks; Bulbospinal Systems; Nonneuronal Cells; Evolution of a Chronic Pain State After Acute Injury; Summary; Encoding of Nociception After Nerve Injury; Events Initiated by Nerve Injury; Origins of Spontaneous Pain State. Site of Origin of Spontaneous Afferent Traffic Mechanisms of Ongoing Activity; Increased Sodium Channel Expression; Decreased K Channel Expression; Inflammatory Products; Origins of Evoke Hyperpathia; Dorsal Root Ganglion Cell Cross Talk; Afferent Sprouting; Loss of Intrinsic GABAergic/Glycinergic Inhibitory Control; Nonneuronal Cells and Nerve Injury; Sympathetic Dependency; Generalization to Many Nerve Injury Pain States; Conclusions; References; 2: Pharmacogenomics of Pain Management; Key Points; Introduction; Background; Functional Genomics of Pain. Pharmacogenomics of Pain Therapy and Its Usefulness in Clinical Practice Genetic Variations in the Prodrug Activation; Genetic Variations in the Elimination of Analgesic Drugs; Genetic Variations in the Transmembrane Transport of Analgesics; Pharmacodynamics of Pain Therapy; Opioid Receptors; Catechol-O-Methyltransferase (COMT); Melanocortin 1 Receptor (MC1R); Cyclooxygenases (COX); Future Direction of Pharmacogenomics in Pain Treatment; Summary; References; 3: Nonsteroidal Anti-inflammatory Drugs; Key Points; Introduction; Mechanism of Action; Pharmacokinetics; Absorption.
• Publisher Details: New York : Springer
• Publication Date: 2015
• Copyright Date: 2015
• Extent: 1 online resource
• Subjects: 610 616.0472 616.8 617.96; Medicine; Chronic pain -- Treatment -- Textbooks; Anesthesiology; Neurology; Pain medicine; Primary care (Medicine); Emergency medicine; Medicine & Public Health; Pain Medicine; Primary Care Medicine; Neurology; Anesthesiology; Chronic Pain -- therapy; Medical -- Family & General Practice; Medical -- Neurology; Medical -- Anesthesiology; General practice; Neurology & clinical neurophysiology; Anaesthetics; Medical -- Pain Medicine; Pain & pain management; Electronic books; Electronic books
• Languages: English
• ISBNs: 1493918184; 9781493918188
• Notes: Note: Includes bibliographical references and index.; Note: Description based on online resource; title from PDF title page (ebrary, viewed April 2, 2015).
• Access Rights: Legal Deposit; Only available on premises controlled by the deposit library and to one user at any one time; The Legal Deposit Libraries (Non-Print Works) Regulations (UK).
• Access Usage: Restricted: Printing from this resource is governed by The Legal Deposit Libraries (Non-Print Works) Regulations (UK) and UK copyright law currently in force.