Raynaud's phenomenon : a guide to pathogenesis and treatment /: a guide to pathogenesis and treatment. ([2015])

• Record Type: Book
• Further Information: Note: Fredrick M. Wigley, Ariane L. Herrick, Nicholas A. Flavahan, editors.
• Editors: Wigley, Fredrick M; Herrick, Ariane L; Flavahan, Nicholas A
• Contents: Foreword: United Kingdom; Foreword: United States of America; Preface; Acknowledgments; Contents; Contributors; 1: Historical Perspective of Raynaud's Phenomenon; Key Points; Milestones; Pathogenetic Mechanisms; Epidemiology; Diagnosis; Treatment; Conclusion; References; 2: Definition, Nomenclature, and Diagnostic Criteria; Key Points; Definition; Nomenclature; Criteria for Classification; Diagnostic Criteria; Summary; References; 3: Epidemiology of Raynaud's Phenomenon; Key Points; Primary RP; Incidence and Prevalence of Primary RP; Risk Factors for Primary RP; Age; Female Sex. Environmental Factors Genetic Factors (Including for Secondary RP); Secondary RP; Incidence and Prevalence of Secondary RP; Aetiology of Secondary RP; Systemic Sclerosis; Other Autoimmune Diseases; Other Systemic Diseases; Neurologic Diseases; Drugs (Chap. 10); Occupational Exposure to Vibration (Chap. 9); Risk and Prognostic Factors for Progression to Systemic Disease; RP as Risk Factor for Digital Ischemia, Gangrene and Auto-amputation; RP as Risk Factor for Other Organ Manifestations; Morbidity and Function; Expert Opinion; Conclusions; References. 4: Thermoregulation: The Normal Structure and Function of the Cutaneous Vascular SystemKey Points; Introduction; General Aspects of the Vascular System and Blood Vessel Wall; Structural and Functional Organization of the Human Cutaneous Circulation; Mechanisms Regulating Blood Flow Responses During Cold Exposure; Modulation of Sympathetic and Adrenergic Constriction; Preclinical Models; The Human Circulation; Secondary Vasomotor Mechanisms; Transient Receptor Potential (TRP) Channels; Brown and Perivascular Adipose Tissue; Gender-Dependent Changes in Cold-Induced Vasoconstriction. 6: Primary Raynaud's PhenomenonKey Points; Introduction; Case History; Definition; Epidemiology; Pathogenesis; History and Examination; Investigations; Treatment; Patient Education/General Measures; Drug Treatment (Table 6.2); Other Treatments; Transition from Primary to Secondary RP; Expert Opinion; References; 7: Raynaud Phenomenon in the Pediatric Age; Key Points; Introduction; Epidemiology Including Secondary Causes; Clinical Features; History; Examination; Investigations; Nailfold Capillaroscopy in Children; Other Imaging Techniques; Predictors of Progression to CTD.
• Publisher Details: New York, NY : Springer
• Publication Date: 2015
• Extent: 1 online resource (xix, 394 pages), illustrations (some color)
• Subjects: 616.1/31; Medicine; Raynaud's disease; Raynaud's disease -- Treatment; HEALTH & FITNESS -- Diseases -- General; MEDICAL -- Clinical Medicine; MEDICAL -- Diseases; MEDICAL -- Evidence-Based Medicine; MEDICAL -- Internal Medicine; Raynaud's disease; Medicine; Health & Biological Sciences; Musculoskeletal System Diseases; Raynaud Disease -- therapy; Medical -- Dermatology; Clinical & internal medicine; Dermatology; Rheumatology; Internal medicine; Dermatology; Medical -- Rheumatology; Rheumatology; Electronic books
• Languages: English
• ISBNs: 9781493915262; 1493915266; 1493915258; 9781493915255
• Related ISBNs: 9781493915255
• Notes: Note: References5: Pathophysiological Regulation of the Cutaneous Vascular System in Raynaud's Phenomenon; Key Points; Introduction; Cutaneous Vascular Responses to Cold Exposure in RP; Mechanisms Contributing to Altered Vasoconstrictor Activity in RP; Sympathetic and Adrenergic Responses; Vascular Mechanisms Underlying the Characteristic Color Changes of RP; Endothelial NO; Endothelin-1 and Endothelial Exocytosis; Others; Structural Changes in Cutaneous Circulation; Endothelial to Mesenchymal Transition; Mechanism-Based Approaches to Treating the Vascular Pathogenesis of RP; References.; Note: Online resource; title from PDF title page (SpringerLink, viewed November 4, 2014).
• Access Rights: Legal Deposit; Only available on premises controlled by the deposit library and to one user at any one time; The Legal Deposit Libraries (Non-Print Works) Regulations (UK).
• Access Usage: Restricted: Printing from this resource is governed by The Legal Deposit Libraries (Non-Print Works) Regulations (UK) and UK copyright law currently in force.