Precision medicine, CRISPR, and genome engineering : moving from association to biology and therapeutics /: moving from association to biology and therapeutics. ([2017])

• Record Type: Book
• Further Information: Note: Stephen H. Tsang, editor ; foreword by George M. Church.
• Editors: Tsang, Stephen H
• Other Names: Church, George M (George McDonald) writer of foreword.
• Contents: Part 1. Introduction to the CRISPR revolution. Viral vectors, engineered cells and the CRISPR revolution / James E. DiCarlo, Anurag Deeconda, and Stephen H. Tsang -- Combined engineered nucleases with adeno-associated viral vectors for therapeutic gene editing / Benjamin E. Epstein and David V. Schaffer -- part 2. CRISPR in model systems. From reductionism to holism: toward a more complete view of development through genome engineering / Rebecca K. Delker and Richard S. Mann -- A transgenic core facility's experience in genome editing revolution / Celvie L. Yuan and Yueh-Chiang Hu -- Genome editing to study Ca²⁺ homeostasis in zebrafish cone photoreceptors / Susan E. Brockerhoff -- CRISPR: from prokaryotic immune systems to plant genome editing tools / Anindya Bandyopadhyay, Shamik Mazumdar, Xiaojia Yin, and William Paul Quick -- part 3. The future of CRISPR. Target discovery for precision medicine using high-throughput genome engineering / Xinyi Guo, Poonam Chitale, and Neville E. Sanjana -- CRISPR in the retina: evaluation of future potential / Galaxy Y. Cho, Sally Justus, Jesse D. Sengillo, and Stephen H. Tsang -- The future of CRISPR applications in the lab, the clinic and society / Soren H. Hough and Ayokunmi Ajetunmobi.
• Publisher Details: Cham, Switzerland : Springer
• Publication Date: 2017
• Copyright Date: 2017
• Extent: 1 online resource (ix, 178 pages), color illustrations
• Subjects: 576.5; 570; Life sciences; Genetic engineering; Genetic engineering; SCIENCE -- Life Sciences -- Evolution; Life Sciences; Regenerative Medicine/Tissue Engineering; Stem Cells; Ophthalmology; Human Genetics; Agriculture; Genetic Engineering; Genetic Engineering; Clustered Regularly Interspaced Short Palindromic Repeats; Genome; Precision Medicine; Science -- Life Sciences -- Cytology; Medical -- Ophthalmology; Medical -- Genetics; Technology & Engineering -- Agriculture -- General; Genetics (non-medical); Ophthalmology; Medical genetics; Agricultural science; Stem cells; Ophthalmology; Human genetics; Agriculture; Science -- Life Sciences -- Biology -- Molecular Biology; Cellular biology (cytology); Electronic books
• Languages: English
• ISBNs: 9783319639048; 3319639048
• Related ISBNs: 9783319639031; 331963903X
• Notes: Note: Includes bibliographical references.; Note: Description based on online resource; title from electronic title page (ScienceDirect, viewed April 13, 2018).
• Access Rights: Legal Deposit; Only available on premises controlled by the deposit library and to one user at any one time; The Legal Deposit Libraries (Non-Print Works) Regulations (UK).
• Access Usage: Restricted: Printing from this resource is governed by The Legal Deposit Libraries (Non-Print Works) Regulations (UK) and UK copyright law currently in force.