The cytoskeleton in health and disease. ([2015])

• Record Type: Book
• Further Information: Note: Heide Schatten, editor.
• Editors: Schatten, Heide
• Contents: Part I: Overview of the cytoskeleton. Brief overview of the cytoskeleton -- Part II: Focus on cytoskeletal interactions. Cytoskeleton dynamics in health and disease: role of molecular switches and rheostats -- Regulation of the cytoskeleton by the rho family of GTPases in hematopoietic stem cells in health and disease -- The role of the cytoskeleton in cell migration, its influence on stem cells and the special role of GFAP in glial functions -- Centrosome-microtubule interactions in health, disease, and disorders -- Cytoskeletal elements and the reproductive success in animals -- Part III: Focus on microtubules. Cytoskeleton and regulation of mitochondrial translocation in mammalian eggs -- Tubulin detyrosination in epithelial cells -- Mutations in adenomatous polyposis coli, their role in cytoskeletal dynamics and cancer onset -- Small GTPases act as cellular switches in the context of cilia -- Part IV: Focus on intermediate filaments. Desmin plays dual structural and regulatory functions through its interaction with partners in muscle -- Desmin filaments and desmin-related myopathy -- Possible functions of intermediate filaments in mammalian ovarian follicles and oocytes -- Part V: Focus on microfilaments. Actin organizing proteins in regulation of osteoclast function -- The role of drebrin-binding stable actin filaments in dendritic spine morphogenesis -- The role of the actin cytoskeleton in cancer and its potential use as a therapeutic target.
• Publisher Details: New York : Springer
• Publication Date: 2015
• Copyright Date: 2015
• Extent: 1 online resource (xii, 395 pages), illustrations (some color)
• Subjects: 571.6/54; Life sciences; Cytoskeleton; SCIENCE -- Life Sciences -- Anatomy & Physiology; Cytoskeleton; Cytoskeleton; Science -- Life Sciences -- Cytology; Cellular biology (cytology); Cell physiology; Cell cycle; Electronic books
• Languages: English
• ISBNs: 9781493929047; 1493929046
• Related ISBNs: 9781493929030; 1493929038
• Notes: Note: Includes bibliographical references and index.; Note: Online resource; title from resource home page (ebrary, viewed December 22, 2015).
• Access Rights: Legal Deposit; Only available on premises controlled by the deposit library and to one user at any one time; The Legal Deposit Libraries (Non-Print Works) Regulations (UK).
• Access Usage: Restricted: Printing from this resource is governed by The Legal Deposit Libraries (Non-Print Works) Regulations (UK) and UK copyright law currently in force.