Discovering and developing molecules with optimal drug-like properties. ([2014])

• Record Type: Book
• Further Information: Note: Allen C. Templeton, Stephen R. Byrn, Roy J. Haskell, Thomas E. Prisinzano, editors.
• Editors: Templeton, Allen C; Byrn, Stephen R; Haskell, Roy J; Prisinzano, Thomas E
• Contents: 1 Developability Assessment and Risk Management During Drug Discovery -- 2 Discovery Formulations -- Approaches and Practices in Early Preclinical Development -- 3 Enabling Discovery Through Leveraging and Miniaturizing Pharmaceutical Principles and Processes -- 4 Diagnosing Biopharmaceutical Limitations -- 5 The Importance of Molecular Design Principles in Delivering High Quality Pharmaceutical Candidates -- 6 Predictive Approaches to Establishing, Understanding, and Communicating Risk with Emphasis on Early Development -- 7 Strategies and Methods for Drug Candidate Phase Optimization in Discovery Space -- 8 Efficient Laboratory Methods to Assess Risk and Design Formulations -- 9 Advanced X-ray Analytical Methods to Understand Structure, Properties and Risk -- 10 Performance and Characterization of Amorphous Solid Dispersions: An Overview -- 11 Hot-Melt Extrusion: The Process-Product-Performance Interplay -- 12 Practical Considerations for Spray Dried Formulation and Process Development -- 13 Nanosizing: "End-to-End" Formulation Strategy for Poorly-Water- Soluble Molecules -- 14 Leveraging Solid State Form and Physiochemical Properties for Early Clinical Formulation Efforts: Opportunities and Challenges during Telcagepant Liquid Capsule Development.
• Publisher Details: New York : Springer
• Publication Date: 2014
• Copyright Date: 2015
• Extent: 1 online resource (xi, 511 pages), illustrations (some color)
• Subjects: 615.19; Medicine; Drugs -- Research; Drugs -- Design; Drug Discovery; MEDICAL -- Pharmacology; Drugs -- Design; Drugs -- Research; Pharmaceutical technology; Medical -- Pharmacy; Pharmaceutical technology; Electronic books
• Languages: English
• ISBNs: 9781493913992; 1493913999; 1493913980; 9781493913985
• Related ISBNs: 9781493913985
• Notes: Note: Online resource; title from PDF title page (Ebsco, viewed November 13, 2014).
• Access Rights: Legal Deposit; Only available on premises controlled by the deposit library and to one user at any one time; The Legal Deposit Libraries (Non-Print Works) Regulations (UK).
• Access Usage: Restricted: Printing from this resource is governed by The Legal Deposit Libraries (Non-Print Works) Regulations (UK) and UK copyright law currently in force.