Lung disease in rheumatoid arthritis. (2018)

• Record Type: Book
• Further Information: Note: Aryeh Fischer, Joyce S. Lee, editors.
• Editors: Fischer, Aryeh; Lee, Joyce S
• Contents: Intro; Preface; Contents; Contributors; Chapter 1: Clinical Overview of Rheumatoid Arthritis; Etiology; Genetic Factors; Environmental Factors; Host Factors; Pathogenesis; Epidemiology; Clinical Presentation: Early Arthritis and Periarthritis; Clinical Manifestations: Late Articular and Periarticular Sequelae; Extra-Articular Manifestations; Laboratory Findings; Radiographic Imaging; Diagnosis, Classification Criteria, and Differential Diagnosis; Clinical Variants; Disease Activity and Disability Measures; Treatment; Prognosis: Morbidity and Mortality; References. Chapter 2: Rheumatoid Arthritis Pathogenesis and PathophysiologyRA Etiology; Genetic Risk; Evolution of the RA Immune Response; Humoral Immunity; Role of T Cells; B Cells; Cytokines as the Final Common Pathway in RA Pathophysiology; Extra-Articular Manifestations of RA; References; Chapter 3: The Lungs as the Site of Initiation of RA; Introduction; Preclinical RA; Autoantibody and Inflammatory Evolution in Preclinical RA; The Natural History of RA Suggests That Initial Autoimmunity Starts Outside of the Joints. The Lung Is a Particularly Important Site of Possible Initiation of RABiologic Machinery Within the Lung to Generate Immune (and Autoimmune) Responses; Epidemiologic Data Linking Inhaled Factors to Risk for RA; Lung Disease in the Absence of or Preceding Synovitis in RA; Generation of RA-Related Autoimmunity Within the Lung in the Absence of Synovitis; Putting It All Together: A Model of RA Where Autoimmunity Starts in the Lung and Later Involves the Joints; Future Directions; Conclusion; References. Chapter 4: The Epidemiology of Rheumatoid Arthritis-ÂƯAssociated Lung DiseaseIntroduction; Challenges of Epidemiologic Studies in RA Lung Disease; Rheumatoid Arthritis-Associated Interstitial Lung Disease; Prevalence and Cumulative Incidence of RA-ILD in Patients Known to Have RA (Table 4.1); Prevalence of RA-ILD in Patients with Respiratory Symptoms; Prevalence of RA-ILD in Unselected Patients; Prevalence of RA-ILD Using CXR, Pulmonary Function Tests (PFTs), and Multimodality Approach; Risk Factors for RA-ILD (Table 4.2); Smoking; Sex; Age; RA Disease Activity. RA Disease DurationRA Treatment; Genetics; RA-Related Antibodies; Rheumatoid Arthritis-Associated Airways Disease; Prevalence and Cumulative Incidence of Airways Disease in RA (Table 4.3); Rheumatoid Arthritis-Associated Pleural Disease; Summary; References; Chapter 5: Risk Factors and Biomarkers of RA-ILD; Introduction; RA-ILD Phenotypes; Risk Factors; Biomarkers; Autoantibodies; Experimental Serum Biomarkers; Alveolar Protein Biomarkers; Other Potential Markers of RA-ILD; Clinical Predictive Modeling; Conclusion; References; Chapter 6: Thoracic Imaging in Rheumatoid Arthritis.
• Publisher Details: Cham, Switzerland : Humana Press
• Publication Date: 2018
• Extent: 1 online resource (x, 178 pages), illustrations (some color)
• Subjects: 616.7/227; Medicine; Rheumatoid arthritis; Lungs -- Diseases; HEALTH & FITNESS -- Diseases -- General; MEDICAL -- Clinical Medicine; MEDICAL -- Diseases; MEDICAL -- Evidence-Based Medicine; MEDICAL -- Internal Medicine; Lungs -- Diseases; Rheumatoid arthritis; Medical -- Rheumatology; Medical -- Critical Care; Rheumatology; Intensive care medicine; Pneumology; Rheumatology; Critical care medicine; Medical -- Pulmonary & Thoracic Medicine; Respiratory medicine; Electronic books
• Languages: English
• ISBNs: 9783319688886
• Related ISBNs: 331968888X; 9783319688879
• Notes: Note: Online resource; title from PDF title page (SpringerLink, viewed February 20, 2018).
• Access Rights: Legal Deposit; Only available on premises controlled by the deposit library and to one user at any one time; The Legal Deposit Libraries (Non-Print Works) Regulations (UK).
• Access Usage: Restricted: Printing from this resource is governed by The Legal Deposit Libraries (Non-Print Works) Regulations (UK) and UK copyright law currently in force.