Autophagy in Health and Disease : Potential Therapeutic Approaches /: Potential Therapeutic Approaches. (2018)

• Record Type: Book
• Further Information: Note: Kursad Turksen, editor.
• Editors: Turksen, Kursad
• Contents: Intro; Preface; Contents; Contributors; Chapter 1: Autophagy and Stem Cells; 1.1 Types and Functions of Autophagy; 1.1.1 Classification and Function of Autophagy; 1.1.2 Characteristics of Autophagy; 1.2 Types and Characteristics of Stem Cells; 1.3 The Regulation of Autophagy in Different Stem Cells; 1.3.1 The Role of Autophagy in Embryonic Stem Cells; 1.3.2 The Effect of Autophagy on Hematopoietic Stem Cells; 1.3.2.1 The Role of Autophagy in Hematopoietic Stem Cells; 1.3.2.2 The Effect of Autophagy on the Regeneration of Hematopoietic Stem Cells 1.3.2.3 The Effect of Autophagy on the Proliferation and Differentiation of Hematopoietic Stem Cells1.3.3 Autophagy and Neural Stem Cells; 1.3.4 Autophagy and Mesenchymal Stem Cells; 1.3.5 Autophagy and Cancer Stem Cells; 1.4 Progress of Autophagy and Stem Cells in Different Diseases; 1.5 Application Prospects and Summary; References; Chapter 2: Fine-Tuning the Stem Cell Fate by Autophagy; 2.1 Stem Cell Differentiation; 2.2 Stem Cells and Autophagy; 2.3 Autophagy in Stem Cell Lineage Commitment and Differentiation; References 4.3 FoxOs in Autophagy and Tissue Homeostasis4.3.1 Autophagy and FoxO Network; 4.3.2 FoxO-Autophagy Axis in Adipocytes and Adipose Tissue; 4.3.3 FoxO-Autophagy Axis in the Liver; 4.3.4 FoxO-Autophagy Axis in the Muscle; 4.3.5 FoxO-Autophagy Axis in the Heart; 4.3.6 FoxO-Autophagy Axis in Other Tissues and Medical Conditions; 4.3.6.1 FoxOs Regulate Autophagy in Neurology; 4.3.6.2 FoxOs Regulate Autophagy in Immunity; 4.3.6.3 FoxOs Regulate Autophagy in Aging; 4.3.6.4 Tumorigenesis and Cancer Cells; 4.4 Conclusions; References; Chapter 5: The Role of mTOR in Osteoclasts; 5.1 Osteoclasts 5.2 Overview of mTOR Signaling5.3 Role of mTOR in Osteoclasts; 5.4 Regulation of mTOR in Osteoclasts; 5.5 Conclusion; References; Chapter 6: Apoptotic Cell Clearance in Gut Tissue: Role of Intestinal Regeneration; 6.1 Introduction; 6.2 Migration of Phagocytes to Apoptotic Cells; 6.3 Recognition of Apoptotic Cells; 6.4 Phagocytosis of Apoptotic Cells; 6.5 Cell Clearance and Anti-inflammatory Response; 6.6 Exclusion and Regeneration of Intestinal Epithelial Cells; 6.7 Autophagy; 6.8 Intestinal Self-Defense and Immune Response; 6.9 Summary; References
• Publisher Details: Cham, Switzerland : Humana Press
• Publication Date: 2018
• Extent: 1 online resource
• Subjects: 571.936; Life sciences; Cell death; Cytology; Autophagic vacuoles; Diseases; SCIENCE / Life Sciences / Anatomy & Physiology; Science -- Life Sciences -- Cytology; Medical -- Pharmacy; Medical -- Endocrinology & Metabolism; Cellular biology (cytology); Pharmaceutical technology; Metabolism; Cell cycle; Cell physiology; Pharmaceutical technology; Metabolic diseases; Electronic books
• Languages: English
• ISBNs: 9783319981468; 3319981463
• Related ISBNs: 9783319981451
• Notes: Note: Online resource; title from PDF title page (EBSCO, viewed October 10, 2018).
• Access Rights: Legal Deposit; Only available on premises controlled by the deposit library and to one user at any one time; The Legal Deposit Libraries (Non-Print Works) Regulations (UK).
• Access Usage: Restricted: Printing from this resource is governed by The Legal Deposit Libraries (Non-Print Works) Regulations (UK) and UK copyright law currently in force.