Aging Research : Methodological Issues /: Methodological Issues. ([2018])

• Record Type: Book
• Further Information: Note: Carmen García-Peña, Luis Miguel Gutiérrez Robledo, Mario Ulises Pérez-Zepeda, editors.
• Editors: García-Peña, María del Carmen; Gutiérrez Robledo, Luis Miguel; Pérez-Zepeda, Mario Ulises
• Contents: Intro; Preface to the Second Edition; Contents; Contributors; Chapter 1: The Need for Differentiated Research Methodology in Aging; 1.1 Introduction; 1.2 A Theoretical Frame for Aging Research; 1.3 Particular Features of Aging Research; 1.3.1 Heterogeneity in Older Adults; 1.3.1.1 Age; 1.3.1.2 Function; 1.3.1.3 Multi-Morbidity; 1.3.2 Animal Models; 1.3.3 The Role of Time; 1.3.4 The Role of Outcomes; 1.3.5 Statistical Approaches; 1.4 Conclusions; References; Chapter 2: The Scientific Method as a Point of Departure in Aging Research; 2.1 Introduction: History and Philosophy of Science 2.2 A Pragmatic Approach to the Scientific Method2.3 The Scientific Method in the Modern Context of Complex Systems and Applied to the Complex Problem of Human Aging; 2.4 Conclusions; References; Chapter 3: Biomedical Research in Aging; 3.1 Introduction; 3.2 Stem Cells in Aging; 3.2.1 Identifying Stem Cells; 3.2.2 Technical Considerations for Studying Stem Cell Aging; 3.3 Genomic Instability, DNA-damage and Telomere Attrition; 3.3.1 Human Disorders of Premature Aging and DNA-damage Repair; 3.3.2 Animal Models for the Study of Premature Aging Driven by DNA-damage; 3.4 Epigenetics of Aging 3.4.1 Histone Alterations3.4.2 Chromatin Reorganization; 3.4.3 DNA Methylation; 3.5 Deregulated Nutrient Sensing; 3.6 Age-related Chronic Inflammation; 3.7 Cellular Senescence in Aging; 3.7.1 Cellular Senescence: Lessons From In vitro Research; 3.7.2 Common Methods for the In vivo Identification of Senescent Cells; 3.7.3 Novel Tools and Models for the Study of Cellular Senescence; 3.8 Conclusions; References; Chapter 4: Geroscience; 4.1 Introduction; 4.2 Geroscience: The Beginning of a New Discipline; 4.3 Advances in Geroscience: Therapies and Interventions 4.4 Biomarkers of Aging and Age-Related Diseases4.4.1 Biomarkers for Neurodegenerative Diseases; 4.4.2 Biomarkers for Muscle Disorders; 4.4.3 Biomarkers for Bone Diseases; 4.5 Perspectives; References; Chapter 5: Descriptive Studies in Clinical Gerontology and Geriatrics; 5.1 Introduction; 5.2 Case Study; 5.3 Case Series; 5.4 Prevalence; 5.5 Other Descriptive Studies; 5.6 Summaries of Descriptive Studies in Aging Research; 5.6.1 Prevalence; 5.6.2 Case Study; 5.6.2.1 Case 1; 5.6.2.2 Case 2; 5.6.3 Case Series; 5.6.4 Ecological Studies; 5.6.5 Surveillance Studies; 5.7 Conclusions; References Chapter 6: Qualitative Research in Gerontology and Geriatrics6.1 Introduction; 6.2 The Niche of Qualitative Research; 6.3 Sampling Alternatives; 6.4 Data Collection Strategies; 6.4.1 Observation; 6.4.2 In-Depth Interviews; 6.4.3 Focal Discussion Groups; 6.4.4 Diaries, Documents and Other Registries; 6.5 Analysis of Qualitative Data; 6.6 Peculiarities of Qualitative Research in Gerontology and Geriatrics; 6.6.1 In-Depth Interviews; 6.6.2 Group Activities; 6.6.3 Observation; 6.7 Limitations of Qualitative Research; 6.8 Enhancing Rigor in Qualitative Research; References
• Publisher Details: Cham, Switzerland : Springer
• Publication Date: 2018
• Extent: 1 online resource
• Subjects: 305.26; Medicine; Aging -- Research -- Methodology; Gerontology -- Research -- Methodology; Geriatrics -- Research -- Methodology; SOCIAL SCIENCE -- Discrimination & Race Relations; SOCIAL SCIENCE -- Minority Studies; Medical -- Geriatrics; Family & Relationships -- Aging; Science -- Study & Teaching; Science -- General; Geriatric medicine; Age groups: the elderly; Teaching of a specific subject; Educational: Sciences, general science; Geriatrics; Aging_xResearch; Science_xStudy and teaching; Medical -- General; Medical research; Electronic books
• Languages: English
• ISBNs: 9783319953878; 3319953877
• Related ISBNs: 9783319953861
• Notes: Note: Includes bibliographical references and index.; Note: Online resource; title from PDF title page (EBSCO, viewed October 2, 2018).; Note: Vendor-supplied metadata.
• Access Rights: Legal Deposit; Only available on premises controlled by the deposit library and to one user at any one time; The Legal Deposit Libraries (Non-Print Works) Regulations (UK).
• Access Usage: Restricted: Printing from this resource is governed by The Legal Deposit Libraries (Non-Print Works) Regulations (UK) and UK copyright law currently in force.