Aging and aging-related diseases : mechanisms and interventions /: mechanisms and interventions. ([2018])

• Record Type: Book
• Further Information: Note: Zhao Wang, editor.
• Editors: Wang, Zhao
• Contents: Intro; Preface; Contents; Contributors; 1: Systems Biology in Aging Research; 1.1 Introduction; 1.2 Data Resource for Systems Biology in Aging Research; 1.2.1 Genomics; 1.2.2 Epigenomics; 1.2.3 Transcriptomics; 1.2.4 Proteomics; 1.2.5 Metabolomics; 1.2.6 Metagenomics; 1.2.7 Phenomics; 1.2.8 Single-Cell/Organism Measurement; 1.3 Data Analysis for Systems Biology in Aging Research; 1.3.1 Network Construction; 1.3.2 Model Aging Systems; 1.4 Conclusions; References; 2: Circular RNA in Aging and Age-Related Diseases; 2.1 Introduction 2.2 CircRNAs in the Physiological Aging Processes2.2.1 CircRNAs Accumulation in the Aged Brain; 2.2.2 CircRNAs Abundant in Skeletal Muscle; 2.2.3 CircRNAs in Fibroblasts and CD8(+)T Cell; 2.2.4 CircRNAs in Caenorhabditis elegans; 2.3 Cancer-Related CircRNAs; 2.3.1 Hepatocellular Carcinoma; 2.3.2 Gastric Cancer; 2.3.3 Colorectal Cancer; 2.3.4 Other Cancers; 2.4 Cardiovascular Disease-Related CircRNAs; 2.4.1 CircRNA in Cardio-Related Disease; 2.4.2 CircRNA in Vascular Disease; 2.5 Diabetes-Related CircRNAs; 2.5.1 CircRNA_000203; 2.5.2 Cdr1as; 2.5.3 Hsa_circ_0054633 2.5.4 Hsa-circRNA11783-22.5.5 CircHIPK3; 2.6 Neurodegenerative Disease-Related CircRNAs; 2.6.1 Glioma Malignancy; 2.6.2 Alzheimer's Disease; 2.7 Conclusions; References; 3: Noncoding RNAs in Cardiovascular Aging; 3.1 Introduction; 3.2 Cardiac Aging; 3.3 Vascular Aging; 3.4 MicroRNAs in Cardiac Aging; 3.5 MicroRNAs in Vascular Aging; 3.6 LncRNAs in Cardiovascular Aging; 3.7 Conclusions; References; 4: Epigenetic Regulation of Vascular Aging and Age-Related Vascular Diseases; 4.1 Introduction; 4.2 Epigenetic Regulation of Vascular Cell Senescence 4.2.1 Changes in Vascular Cells During the Vascular Aging Process4.2.2 Epigenetic Regulation of Vascular Cell Senescence; 4.3 Epigenetic Regulation of Age-Associated Vascular Dyshomeostasis; 4.3.1 Oxidative Stress; 4.3.2 Calcification; 4.3.3 Inflammation; 4.3.4 Cross Talk Between Vascular Cells and Vascular Dyshomeostasis; 4.4 Epigenetic Regulation of Age-Associated Vascular Remodeling; 4.5 Age-Related Vascular Diseases; 4.6 Epigenetic-Targeted Therapeutic Strategies for the Treatment of Vascular Aging and Age-Related Vascular Diseases; 4.7 Conclusion and Perspective; References
• Publisher Details: Singapore : Springer
• Publication Date: 2018
• Extent: 1 online resource, illustrations (some color)
• Subjects: 612.67; Medicine; Aging; Geriatrics; Older people -- Diseases; Human physiology; MEDICAL / Physiology; SCIENCE / Life Sciences / Human Anatomy & Physiology; Medical -- Geriatrics; Medical -- Physiology; Geriatric medicine; Physiology; Science -- Life Sciences -- Biology -- Molecular Biology; Medical research; Electronic books
• Languages: English
• ISBNs: 9789811311178
• Related ISBNs: 981131117X; 9789811311161; 9811311161
• Notes: Note: Includes bibliographical references.; Note: Online resource; title from PDF title page (EBSCO, Sept. 26, 2018).
• Access Rights: Legal Deposit; Only available on premises controlled by the deposit library and to one user at any one time; The Legal Deposit Libraries (Non-Print Works) Regulations (UK).
• Access Usage: Restricted: Printing from this resource is governed by The Legal Deposit Libraries (Non-Print Works) Regulations (UK) and UK copyright law currently in force.