Store-operated Ca² entry (SOCE) pathways : emerging signaling concepts in human (patho)physiology /: emerging signaling concepts in human (patho)physiology. ([2017])

• Record Type: Book
• Other Titles: Store-operated calcium two plus entry (SOCE) pathways; SOCE pathways
• Further Information: Note: Klaus Groschner, Wolfgang F. Graier, Christoph Romanin, editors.
• Editors: Groschner, Klaus; Graier, Wolfgang F; Romanin, Christoph
• Contents: SOCE: fundamental mechanistic concepts. Introduction / James W. Putney -- The STIM-Orai pathway: STIM-Orai structures: isolated and in complex / Jinhui Zhu, Qingping Feng, Peter B. Stathopulos -- The STIM-Orai pathway: Orai, the pore-forming subunit of the CRAC channel / Aparna Gudlur, Patrick G. Hogan -- The STIM-Orai pathway: the interactions between STIM and Orai / Marc Fahrner, Rainer Schindl, Martin Muik, Isabella Derler, Christoph Romanin -- The STIM-Orai pathway: conformational coupling between STIM and Orai in the activation of store-operated Ca2+ entry / Robert M. Nwokonko, Xiangyu Cai, Natalia A. Loktionova, Youjun Wang, Yandong Zhou [and others] -- The STIM-Orai pathway: regulation of STIM and Orai by thiol modifications / Barbara A. Niemeyer -- The STIM-Orai pathway: light-operated Ca2+ entry through engineered CRAC channels / Guolin Ma, Shufan Wen, Yun Huang, Yubin Zhou -- STIM-TRPpathways and microdomain organization: Ca2+ influx channels: the Orai-STIM1-TRPC complexes / Dora Bodnar, Woo Young Chung, Dongki Yang, Jeong Hee Hong, Archana Jha, Shmuel Muallem -- STIM-TRP pathways and microdomain organization: contribution of TRPC1 in store-operated Ca2+ entry: impact on Ca2+ signaling and cell function / Hwei Ling Ong, Indu S. Ambudkar -- STIM-TRP pathways and microdomain organization: auxiliary proteins of the STIM/Orai complex / Jonathan Pacheco, Luis Vaca -- SOCE: crosstalk between organelle and cellular compartments. introduction / Alexei V. Tepikin -- New aspects of the contribution of ER to SOCE regulation: the role of the ER and ER-plasma membrane junctions in the regulation of SOCE / Hayley Dingsdale, Emmanuel Okeke, Lee Haynes, Gyorgy Lur, Alexei V. Tepikin -- New aspects of the contribution of ER to SOCE regulation: TRPC proteins as a link between plasma membrane ion transport and intracellular Ca2+ stores / Alexis Bavencoffe, Michael Xi Zhu, Jin-bin Tian -- The role of mitochondria in the activation/maintenance of SOCE: store-operated Ca2+ entry and mitochondria / András Spät, Gerg̲ Szanda -- The role of mitochondria in the activation/maintenance of SOCE: membrane contact sites as signaling hubs sustaining store-operated Ca2+ entry / Nicolas Demaurex, Daniele Guido -- The role of mitochondria in the activation/maintenance of SOCE: the contribution of mitochondrial Ca2+ uptake, mitochondrial motility, and location to store-operated Ca2+ entry / Roland Malli, Wolfgang F. Graier -- Tissue specificity: the role of organellar membrane nanojunctions in smooth muscle Ca2+ signaling / Nicola Fameli, A. Mark Evans, Cornelis van Breemen -- Tissue specificity: SOCE: implications for Ca2+ handling in endothelial cells / Lothar A. Blatter -- Tissue specificity: store-operated Ca2+ entry in cardiac myocytes / Martin D. Bootman, Katja Rietdorf -- SOCE: molecular and cellular (patho)physiology. Introduction: overview of the pathophysiological implications of store-operated calcium entry in mammalian cells / Juan A. Rosado -- Immunological disorders: regulation of Ca2+ signaling in T lymphocytes / Sonal Srikanth, Jin Seok Woo, Zuoming Sun, Yousang Gwack -- Cardiovascular and hemostatic disorders: role of STIM and Orai proteins in vascular disorders / Jyoti Tanwar, Mohamed Trebak, Rajender K. Motiani -- Cardiovascular and hemostatic disorders: SOCE and Ca2+ handling in platelet dysfunction / Jose J. Lopez, Gines M. Salido, Juan A. Rosado -- Cardiovascular and hemostatic disorders: SOCE in cardiovascular cells: emerging targets for therapeutic intervention / Klaus Groschner, Niroj Shrestha, Nicola Fameli -- Cardiac remodeling and disease: SOCE and TRPC signaling in cardiac pathology / Petra Eder -- Cardiac remodeling and disease: current understanding of STIM1/Orai1-mediated store-operated Ca2+ entry in cardiac function and pathology / Fiona Bartoli, Jessica Sabourin -- Neurological and motor disorders: neuronal store-operated Ca2+ signaling: an overview and its function / Sunitha Bollimuntha, Biswaranjan Pani, Brij B. Singh -- Neurological and motor disorders: TRPC in the skeletal muscle / Sophie Saüc, Maud Frieden -- Fertility: store-operated Ca2+ entry in germ cells: role in egg activation / Zoltan Machaty, Chunmin Wang, Kiho Lee, Lu Zhang -- Metabolic disorders and cancer: hepatocyte store-operated Ca2+ channels in nonalcoholic fatty liver disease / Eunüs S. Ali, Grigori Y. Rychkov, Greg J. Barritt -- Metabolic disorders and cancer: store-operated Ca2+ entry in cancer: focus on IP3R-mediated Ca2+ release from intracellular stores and its role in migration and invasion / Abigael Ritaine, George Shapovalov, Natalia Prevarskaya.
• Publisher Details: Cham, Switzerland : Springer
• Publication Date: 2017
• Copyright Date: 2017
• Extent: 1 online resource (xxix, 645 pages), illustrations (chiefly color)
• Subjects: 616.804427; Life sciences; Calcium channels; Cellular signal transduction; Intracellular calcium; HEALTH & FITNESS -- Diseases -- General; MEDICAL -- Clinical Medicine; MEDICAL -- Diseases; MEDICAL -- Evidence-Based Medicine; MEDICAL -- Internal Medicine; Calcium channels; Cellular signal transduction; Intracellular calcium; Calcium Signaling; Disease -- genetics; Medical -- Biochemistry; Science -- Life Sciences -- Biophysics; Medical -- Cardiology; Biochemistry; Biophysics; Cardiovascular medicine; Cytology; Biochemistry; Cardiology; Science -- Life Sciences -- Biology -- Molecular Biology; Cellular biology (cytology); Electronic books
• Languages: English
• ISBNs: 9783319577326; 3319577328
• Related ISBNs: 9783319577319; 331957731X
• Notes: Note: Includes bibliographical references and index.; Note: Online resource; title from electronic title page (SpringerLink, viewed September 19, 2017).
• Access Rights: Legal Deposit; Only available on premises controlled by the deposit library and to one user at any one time; The Legal Deposit Libraries (Non-Print Works) Regulations (UK).
• Access Usage: Restricted: Printing from this resource is governed by The Legal Deposit Libraries (Non-Print Works) Regulations (UK) and UK copyright law currently in force.