Lipidomics in health & disease : methods & application /: methods & application. (2018)
- Record Type:
- Book
- Title:
- Lipidomics in health & disease : methods & application /: methods & application. (2018)
- Main Title:
- Lipidomics in health & disease : methods & application
- Further Information:
- Note: Xiangdong Wang, Duojiao Wu, Huali Shen, editors.
- Editors:
- (Professor of clinical bioinformatics), Wang, Xiangdong
Wu, Duojiao
Shen, Huali - Contents:
- Intro; Contents; Chapter 1: Clinical Lipidomics: A Critical Approach for Disease Diagnosis and Therapy; 1.1 Values of Disease Specificity; 1.2 Values of Disease Biomarkers; 1.3 Monitoring Disease Severity; 1.4 Integration with Clinical Phenomes; References; Chapter 2: The Role of Lipid Metabolism in the Development of Lung Cancer; 2.1 Introduction; 2.2 Natural Lipid Metabolism in Mammalian Cells; 2.3 Alteration of Lipid Metabolism in Lung Cancer; 2.4 Lipid Synthetase and Lung Cancer; 2.4.1 ATP Citrate Lyase (ACLY); 2.4.2 Acetyl-CoA Carboxylase (ACC); 2.4.3 Fatty Acid Synthase (FASN) 2.4.4 Acyl-Coenzyme A (CoA) Synthetase Long-Chain Family (ACSL)2.4.5 Stearoyl-CoA Desaturase 1 (SCD1); 2.5 The Function of Lipid Membrane and Lung Cancer; 2.6 Lipid Signaling Molecules and Lung Cancer; 2.7 Lipid and Autophagy in Lung Cancer; 2.8 Lipid Metabolism and Hypoxia in Lung Cancer; 2.9 Lipid Metabolism Drugs for Lung Cancer; 2.10 Conclusion; Reference; Chapter 3: Bioinformatics of Embryonic Exposures: Lipid Metabolism and Gender as Biomedical Variables; 3.1 Introduction; 3.1.1 Development; 3.1.2 Environmental Exposures and Cardiovascular Defects; 3.1.3 Prevention by Folic Acid 3.2 Experimental Background Leading to Bioinformatic Analyses3.2.1 Mice; 3.2.2 Control Folic Acid and High Folic Acid Diets; 3.2.3 Experimental Groups; 3.2.4 Microarrays; 3.3 Bioinformatic Analysis; 3.4 Lipid Metabolism and Gender; 3.4.1 Lipid Metabolism and Development; 3.4.2 Embryonic Yolk Sac/PlacentalIntro; Contents; Chapter 1: Clinical Lipidomics: A Critical Approach for Disease Diagnosis and Therapy; 1.1 Values of Disease Specificity; 1.2 Values of Disease Biomarkers; 1.3 Monitoring Disease Severity; 1.4 Integration with Clinical Phenomes; References; Chapter 2: The Role of Lipid Metabolism in the Development of Lung Cancer; 2.1 Introduction; 2.2 Natural Lipid Metabolism in Mammalian Cells; 2.3 Alteration of Lipid Metabolism in Lung Cancer; 2.4 Lipid Synthetase and Lung Cancer; 2.4.1 ATP Citrate Lyase (ACLY); 2.4.2 Acetyl-CoA Carboxylase (ACC); 2.4.3 Fatty Acid Synthase (FASN) 2.4.4 Acyl-Coenzyme A (CoA) Synthetase Long-Chain Family (ACSL)2.4.5 Stearoyl-CoA Desaturase 1 (SCD1); 2.5 The Function of Lipid Membrane and Lung Cancer; 2.6 Lipid Signaling Molecules and Lung Cancer; 2.7 Lipid and Autophagy in Lung Cancer; 2.8 Lipid Metabolism and Hypoxia in Lung Cancer; 2.9 Lipid Metabolism Drugs for Lung Cancer; 2.10 Conclusion; Reference; Chapter 3: Bioinformatics of Embryonic Exposures: Lipid Metabolism and Gender as Biomedical Variables; 3.1 Introduction; 3.1.1 Development; 3.1.2 Environmental Exposures and Cardiovascular Defects; 3.1.3 Prevention by Folic Acid 3.2 Experimental Background Leading to Bioinformatic Analyses3.2.1 Mice; 3.2.2 Control Folic Acid and High Folic Acid Diets; 3.2.3 Experimental Groups; 3.2.4 Microarrays; 3.3 Bioinformatic Analysis; 3.4 Lipid Metabolism and Gender; 3.4.1 Lipid Metabolism and Development; 3.4.2 Embryonic Yolk Sac/Placental Development and Gender; 3.5 Gender and Heart Defects; 3.6 Future Directions; References; Chapter 4: An Evaluation of Multivariate Data Analysis Models for Lipidomic Parameters from Patients with Metabolic Syndrome Undergoing Remedial Treatment; 4.1 Introduction 4.2 Measured Parameters of Met S Change Over Time During Intervention4.2.1 Descriptive Statistics of the Serum Lipid Fatty Acid Composition; 4.2.2 Multivariate Statistics and Modeling of the Serum Lipid Fatty Acid Composition; 4.3 The Search for Significant Explicative Variables of the Metabolic Condition During Lifestyle Intervention; 4.3.1 Correlations of Circulating Lipid Status with the Fatty Acid Composition; 4.3.2 Investigation of Lipid Fatty Acids Versus Dietary Intakes; 4.4 Conclusions; References Chapter 5: Lipidomics in Carotid Artery Stenosis: Further Understanding of Pathology and Treatment5.1 Introduction; 5.2 Lipidomics in Carotid Stenosis; 5.3 Biomarkers; 5.3.1 HDL-C & LDL-C; 5.3.2 Glycerophospholipid and Sphingolipids; 5.3.3 Omega-6 and Omega-3 Polyunsaturated Fatty Acid; 5.4 Lipid Profile in Plaques; 5.5 Platelet; 5.6 Radox Biology; 5.7 Extra Cellular Matrix; 5.8 Treatment; 5.9 Lipidomics Technology in Carotid Stenosis; 5.10 Perspective and Summary; References; Chapter 6: Metabolomics of Immunity and Its Clinical Applications; 6.1 Introduction; 6.2 Fatty Acid Metabolism … (more)
- Publisher Details:
- Singapore : Springer
- Publication Date:
- 2018
- Extent:
- 1 online resource
- Subjects:
- 612/.01577
Medicine
Lipids
Human physiology
Oncology
MEDICAL / Physiology
SCIENCE / Life Sciences / Human Anatomy & Physiology
Medical -- Physiology
Science -- Life Sciences -- Biochemistry
Medical -- Oncology
Physiology
Lipids
Oncology
Science -- Life Sciences -- Biology -- Molecular Biology
Medical research
Electronic books - Languages:
- English
- ISBNs:
- 9789811306204
9811306206 - Related ISBNs:
- 9789811306198
9811306192 - Notes:
- Note: Online resource; title from PDF title page (SpringerLink, viewed September 6, 2018).
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- Legal Deposit; Only available on premises controlled by the deposit library and to one user at any one time; The Legal Deposit Libraries (Non-Print Works) Regulations (UK).
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- Available online (eLD content is only available in our Reading Rooms) ↗
- Physical Locations:
- British Library HMNTS - ELD.DS.325714
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- 02_333.xml