Histologic basis of ocular disease in animals. (2019)

• Record Type: Book
• Further Information: Note: Bruce Grahn, Robert Peiffer, Brian Wilcock.
• Authors: Grahn, Bruce H; Jr, Peiffer, Robert L; Wilcock, Brian P
• Contents: Foreword xiii Acknowledgements xv 1 Fixation and processing of ocular tissues 1 Fixatives 1 Fixation and sectioning artifacts 2 Fixation techniques 3 Trimming the fixed globe 5 Electron microscopy 13 References 14 2 General pathology of the eye 15 Adaptations characterized by changes in cell size, number, or appearance 15 Neoplasia 19 Nomenclature 23 Distinguishing benign from malignant 25 Prognostication 27 Unsuccessful adaptation: cellular degeneration, necrosis, and apoptosis 27 Calcification, pigmentation, and cystic change 30 Ocular inflammation 32 Ocular manifestations of acute inflammation 34 Chronic inflammation 39 Ocular manifestations of chronic inflammation 39 Immune privilege 41 Lymphocytic–plasmacytic endophthalmitis 42 The sequelae of intraocular inflammation and other injuries 43 Limited regenerative ability 43 Susceptibility to scarring 43 Further reading 46 3 Congenital anomalies 49 Introduction 49 Defective organogenesis 50 Defective early organogenesis 50 Anophthalmos and cystic globe 53 Anophthalmos and microphthalmos 54 Cyclopia and synophthalmos 56 Congenital anomalies of lens 56 Congenital retinal nonattachment 63 Aniridia – iridal hypoplasia or aplasia 63 Coloboma 63 Defective later organogenesis 64 Neurectodermal defects 64 Multifocal retinopathies 71 Multiple ocular anomalies (MOA) in Rocky Mountain horses 71 Anomalies of surface ectodermal origin that develop during later organogenesis 73 Congenital adnexal cysts 73 Dermoids 73 Defects of neural crest migration and mesenchymal differentiation that develop in later organogenesis 73 Congenital corneal disease 73 Congenital disorders of neurocrest and mesenchymal tissues that manifest in the uvea during later organogenesis 74 Persistent pupillary membranes (PPMs) 74 Congenital glaucoma 75 Uveal hypoplasia 78 Collie eye anomaly (CEA) and related defects 78 Persistence of embryonic vasculature 81 References 83 4 Histopathology of ocular trauma 89 Perforating and penetrating wounds of the globe and ocular tissues 89 Perforating wounds of the globe 89 Traumatic intraocular hemorrhage 89 Expulsive subchoroidal hemorrhage 90 Sequelae of intraocular hemorrhage 90 Posttraumatic inflammation 95 Phacoclastic endophthalmitis and traumatic cataract 95 Infectious endophthalmitis 95 Trauma to individual ocular tissues 95 Orbit and optic nerve 95 Cornea/sclera 95 Uvea 100 Lens 101 Vitreous and retina 101 Globe as a whole 101 Reaction to foreign materials 101 Complications of ocular surgery 102 Chemical and thermal burns 102 Effects of radiant energy 103 References 103 5 Diseases of the eyelid, conjunctiva, lacrimal, and nasolacrimal systems 105 Eyelids 105 Structural disorders 105 Dermoids 105 Hamartomas 105 Subconjunctival fat prolapse 105 Entropion, ectropion, and medial canthal pocket syndrome 105 Distichiasis, districhiasis, and ectopic cilia 106 Inflammatory disease 108 Pyogranulomatous (granulomatous) blepharitis 108 Juvenile sterile granulomatous dermatitis and lymphadenitis (juvenile cellulitis) 110 Chalazion 110 Medial canthal erosion syndrome 111 Proliferative pox virus blepharitis in birds 111 Parasitic eyelid disorders 111 Demodicosis 111 Cnemidocoptes pilae (scaly beak) infestation of avian species 113 Eyelid tumors and neoplasms 113 Cystic apocrine hyperplasia (hidrocystomas, sudoriferous cysts, and apocrine cysts) 113 Granular cell tumor 113 Meibomian (tarsal gland) adenoma 115 Melanocytoma and melanoma 115 Histiocytoma 118 Mast cell tumor 118 Peripheral nerve sheath tumors 118 Equine sarcoid 121 Squamous cell carcinoma 122 Diseases of the conjunctiva 123 General pathology of the conjunctiva 124 Congenital conjunctival abnormalities 124 Infectious conjunctivitis 126 Herpesvirus 126 Chlamydophila (chlamydia) 126 Rickettsia rickettsi 126 Moraxella bovis 126 Parasitic conjunctivitis 126 Noninfectious inflammatory disease 127 Episclerokerataconjunctivitis 127 Lipogranulomatous conjunctivitis of cats 127 Eosinophilic conjunctivitis 128 Miscellaneous conjunctival disorders 128 Conjunctival overgrowth in rabbits (pseudopterygium) 128 Membranous (ligneous) conjunctivitis 129 Conjunctival neoplasms 129 Conjunctival lymphoma 129 Conjunctival mast cell tumors 130 Conjunctival melanoma and melanocytoma 130 Viral papillomas 133 Conjunctiva squamous papilloma 133 Conjunctival squamous cell carcinoma 133 Conjunctival vascular neoplasia 133 Miscellaneous neoplasms of the third eyelid 133 Lacrimal and nasolacrimal disorders 136 Neoplasms of the gland of the third eyelid 136 Prolapsed gland of the third eyelid 138 Keratoconjunctivitis sicca (KCS) 138 Dacryops and canaliculops 138 References 138 6 Diseases of the cornea 143 Corneal wound healing 143 Epithelial wound healing 143 Stromal wound healing 147 Endothelial wound healing 149 Epithelial and fibrous ingrowth 151 Healing of corneal grafts 152 Nonspecific corneal responses to insult 152 Corneal vascularization 152 Corneal pigmentation 154 Corneal edema 154 Keratitis 154 Epithelial alterations of keratitis 154 Stromal alterations of keratitis 156 Endothelialitis 158 Specific inflammatory corneal disease 159 Immune‐mediated nonulcerative keratitis 159 Immune‐mediated ulcerative keratitis 159 Superficial punctate keratitis (punctate erosive corneal dystrophy) 159 Chronic superficial keratitis (pannus) 159 Eosinophilic keratitis 161 Miscellaneous corneal disorders: corneal sequestrum, indolent corneal ulceration, corneal dystrophy, corneal lipid infiltrates, and corneal degeneration 161 Corneal sequestrum 161 Indolent ulceration (boxer ulcer, spontaneous corneal epithelial defects) 164 Corneal dystrophies, corneal lipid infiltrates, and corneal calcific/lipid degeneration 165 Miscellaneous corneal disease 167 Corneal neoplasia 172 References 177 7 Diseases of the episclera and sclera 181 Primary episcleral and scleral inflammatory disorders: a brief introduction 181 Secondary scleritis 181 Scleral neoplasia 182 Limbal melanocytoma 184 Episcleritis (episclerokeratitis, episclerokeratoconjunctivitis) 185 Scleritis and necrotizing scleritis a continuum or separate conditions? 189 Non‐necrotizing scleritis 193 Necrotizing scleritis 195 Parasitic episcleral disease (onchocerca vulpis/lienalis) 195 References 196 8 Histologic manifestations of disorders of the uvea 197 Normal aging changes 203 Degenerative diseases of the uvea 205 Uveal atrophy 205 Uveal cysts 205 Cystoid degeneration of the pars plana ciliary epithelium 205 P
• Publisher Details: Hoboken, NJ : Wiley-Blackwell
• Publication Date: 2019
• Extent: 1 online resource
• Subjects: 636.089/77; Veterinary ophthalmology; TECHNOLOGY & ENGINEERING / Agriculture / Animal Husbandry; Veterinary ophthalmology; Eye Diseases -- veterinary; Eye Diseases -- pathology; Eye -- pathology; Animals, Domestic; Electronic books
• Languages: English
• ISBNs: 9781118388785; 9781119108603; 1119108608; 9781118388792; 1118388798
• Related ISBNs: 111838878X; 9781118388778
• Notes: Note: Includes bibliographical references and index.; Note: Online resource; title from PDF title page (EBSCO, viewed September 10, 2018)
• Access Rights: Legal Deposit; Only available on premises controlled by the deposit library and to one user at any one time; The Legal Deposit Libraries (Non-Print Works) Regulations (UK).
• Access Usage: Restricted: Printing from this resource is governed by The Legal Deposit Libraries (Non-Print Works) Regulations (UK) and UK copyright law currently in force.