Zinc finger proteins : methods and protocols /: methods and protocols. (2018)

• Record Type: Book
• Further Information: Note: Edited by Jia Liu.
• Editors: Liu, Jia
• Contents: Part I Chapter 1 PRDM14, a zinc finger protein, regulates cancer stemness Chapter 2 Computational methods for analysis of the DNA-binding preferences of Cys2His2 zinc finger proteins Chapter 3 Design and application of mA-specific Zinc finger proteins for the readout of DNA methylation Chapter 4 Enhanced manipulation of human mitochondrial DNA heteroplasmy in vitro using tunable mtZFN technology Chapter 5 Engineering RNA-binding proteins by modular assembly of RanBP2-type Zinc Fingers Chapter 6 Design of a system for monitoring ubiquitination activities of E2 enzymes using engineered RING finger proteins Chapter 7 Directed evolution of targeted recombinases for genome engineering Chapter 8 Optical recording of cellular zinc dynamics with zinc finger based biosensors Chapter 9 Delivery of superoxide dismutase using Cys2-His2 zinc-finger proteins Chapter 10 Genome editing of MSCs as a platform for cell therapy Part II Chapter 11 Integrated multimodal evaluation of genotoxicity in ZFN-modified primary human cells Chapter 12 Selection and characterization of DNA aptamers against FokI nuclease domain Chapter 13 An improved genome engineering method using surrogate reporter-coupled suicidal ZFNs Part III Chapter 14 Non-transgenic approach to deliver ZFNs in seeds for targeted genome engineering Chapter 15 Gene editing in channel catfish via double electroporation of zinc finger nucleases Chapter 16 Delivery of mtZFNs into early mouse embryos Chapter 17 Stereotaxic surgery and viral-delivery of zinc finger epigenetic editing tools in rodent brain Chapter 18 In-vivo applications of cell-penetrating zinc finger transcription factors Chapter 19 Manufacturing and delivering genome-editing proteins.
• Publisher Details: New York, NY : Humana Press
• Publication Date: 2018
• Extent: 1 online resource (xii, 276 pages), illustrations (some color)
• Subjects: 572/.6; Medicine; Zinc-finger proteins -- Laboratory manuals; Human genetics; Medical -- Genetics; Medical genetics; Electronic books
• Languages: English
• ISBNs: 9781493987993; 1493987992
• Related ISBNs: 9781493987986
• Notes: Note: Online resource; title from PDF title page (SpringerLink, viewed September 5, 2018).
• Access Rights: Legal Deposit; Only available on premises controlled by the deposit library and to one user at any one time; The Legal Deposit Libraries (Non-Print Works) Regulations (UK).
• Access Usage: Restricted: Printing from this resource is governed by The Legal Deposit Libraries (Non-Print Works) Regulations (UK) and UK copyright law currently in force.