Physiological assessment of coronary stenoses and the microcirculation. (2017)

• Record Type: Book
• Further Information: Note: Edited by Javier Escaned, Justin Davies.
• Editors: Escaned, Javier; Davies, Justin
• Contents: FOREWORD -- INTRODUCTION -- Part 1. The Coronary Circulation in Health and Disease -- STRUCTURE AND PHYSIOLOGY OF THE CORONARY CIRCULATION -- A historical perspective on coronary circulation -- The anatomy of epicardial, coronary arteries and veins -- The structure of transmural vessels and coronary microcirculation -- Regulation of coronary blood flow -- Myocardial metabolism and blood supply -- Coronary capacitance and the myocardial pump model -- Extravascular compression and vascular waterfalls -- Extrinsic neural control of blood flow -- Hemodynamic effects of epicardial stenoses -- Modification of shear stress by stenoses -- Phasic characteristics in coronary blood flow -- PATHOLOGICAL CHANGES IN CORONARY CIRCULATION -- Epicardial coronary stenosis -- Microvascular remodelling -- Microvascular obstruction -- Extravascular compression of the microcirculation -- Endothelial dysfunction -- Collateral development -- EFFECT OF SPECIFIC PATHOLOGIES ON EPICARDIAL VESSELS AND THE MICROCIRCULATION -- Hypertension and left ventricular hypertrophy -- Diabetes -- Dyslipidemia -- Atherosclerosis. Acute coronary syndromes -- Atherosclerosis. Chronic ischemia -- Acute and chronic effects of percutaneous coronary interventions -- Valvular heart disease -- Part II. Invasive Assessment of the Coronary Circulation in the Catheterization Laboratory -- FRACTIONAL FLOW RESERVE (FFR) -- Understanding fractional flow reserve -- Current evidence on FFR as a clinical tool -- Application of fractional flow reserve to specific stenosis subsets -- INSTANTANEOUS WAVE FREE RATIO (iFR) -- Physiological principles of iFR -- Validation of iFR. Clinical registries -- Application of iFR in clinical scenarios -- CORONARY FLOW RESERVE -- Understanding coronary flow reserve -- Use of Doppler-tipped guidewires to calculate coronary flow reserve -- Relative and adjusted coronary flow reserve -- Use of the thermodilution principle to calculate coronary flow reserve -- INDICES OF CORONARY RESISTANCE -- Understanding indices of coronary resistance -- Stenosis resistance estimated from pressure-flow relationships -- Myocardial resistance estimated with thermodilution and pressure -- Microcirculatory resistance calculated from intracoronary pressure and Doppler -- Integration of pressure and flow indices of coronary stenosis severity -- WAVE INTENSITY ANALYSIS -- Understanding wave intensity analysis -- Wave patterns in coronary flow in health and disease -- Changes in WIA coronary patterns during trans-arterial valve implantation -- ASSESSMENT OF ENDOTHELIAL DYSFUNCTION -- Understanding endothelial modulation of vascular tone -- Assessment of endothelial dysfunction with acetylcholine challenge -- Other methods to assess endothelial dysfunction -- RESEARCH MODELS -- Relevant differences between coronary circulation in human and experimental animal models -- Computerised fluid dynamics applied to modelling of coronary circulation.
• Publisher Details: London : Springer
• Publication Date: 2017
• Extent: 1 online resource
• Subjects: 616.12; Medicine; Coronary arteries -- Stenosis; Microcirculation; Interventional radiology; Cardiology; HEALTH & FITNESS -- Diseases -- General; MEDICAL -- Clinical Medicine; MEDICAL -- Diseases; MEDICAL -- Evidence-Based Medicine; MEDICAL -- Internal Medicine; Cardiology; Coronary arteries -- Stenosis; Interventional radiology; Microcirculation; Cardiology; Coronary Stenosis; Medical -- Biochemistry; Medical -- Diagnostic Imaging; Medical -- Radiology & Nuclear Medicine; Radiology; Radiology, Medical; Medical -- Cardiology; Cardiovascular medicine; Electronic books
• Languages: English
• ISBNs: 9781447152453; 1447152441; 9781447152446
• Related ISBNs: 144715245X; 9781447152446; 1447152441
• Notes: Note: Includes bibliographical references and index.; Note: Online resource, title from PDF title page (SpringerLink, viewed January 10, 2018).
• Access Rights: Legal Deposit; Only available on premises controlled by the deposit library and to one user at any one time; The Legal Deposit Libraries (Non-Print Works) Regulations (UK).
• Access Usage: Restricted: Printing from this resource is governed by The Legal Deposit Libraries (Non-Print Works) Regulations (UK) and UK copyright law currently in force.