Nitric oxide and other small signalling molecules. (2018)

• Record Type: Book
• Further Information: Note: Edited by Robert K. Poole.
• Editors: Poole, Robert K
• Contents: Front Cover; Nitric Oxide and Other Small Signalling Molecules; Copyright; Contents; Contributors; Preface; References; Chapter One: Reactive Cysteine Persulphides: Occurrence, Biosynthesis, Antioxidant Activity, Methodologies, and Bacterial ...; 1. Introduction; 2. Occurrence; 3. Biosynthesis; 4. Antioxidant Activity; 5. Methodologies; 5.1. LC-MS/MS; 5.2. Fluorescent Probes; 5.3. Proteomics; 6. Cysteine Persulphides in Bacterial Signalling; 7. Conclusion; Acknowledgements; References; Chapter Two: Nitric Oxide Signalling in Yeast; 1. Introduction; 2. Nitric Oxide as a Biomolecule Modifier 3. NO Biosynthesis3.1. NO Synthase; 3.2. Nitrite Reductase; 4. NO Detoxification; 4.1. Nitric Oxide Dioxygenase; 4.2. S-Nitrosoglutathione Reductase; 5. Physiological Role of NO in Yeast (Dual Effects); 5.1. Beneficial Effects of NO Signalling; 5.2. Deleterious Effects of NO Signalling; 6. Conclusions; 7. Future Perspectives; Acknowledgements; References; Further Reading; Chapter Three: The Inflammasome: Regulation of Nitric Oxide and Antimicrobial Host Defence; 1. Introduction; 2. NO Is an Effector Molecule in Antimicrobial Host Defence; 3. NOD-Like Receptors; 4. The Inflammasome 5. The NLRP1 Inflammasome6. The NLRP3 Inflammasome; 7. The NAIP/NLRC4 Inflammasome; 8. The AIM2 Inflammasome; 9. Pyrin Inflammasome; 10. Other Inflammasome Complexes; 11. Noncanonical Inflammasome Activation; 12. The Inflammasome in Antimicrobial Host Defence; 13. Inflammasomes in the Regulation of Intestinal Microbiome and Inflammatory Disorders; 14. Involvement of NO in the Effector Mechanism of Inflammasome-Mediated Host Defence; 15. Reciprocal Regulation of the Inflammasome by NO; 16. Concluding Remarks; References Chapter Four: Nitric Oxide, an Old Molecule With Noble Functions in Pseudomonas aeruginosa Biology1. Introduction; 2. Anaerobic Respiration, a Leaky Process for NO Production; 2.1. Overview of Denitrification; 2.2. Chemical and Enzymatic Production of NO; 2.3. Nitric Oxide Reductase, Another Enzyme That Controls NO Production; 3. Regulation of Denitrification; 3.1. Signalling Network; 3.2. Roles of Quorum Sensing; 4. NO, an Important Molecule That Influences P. aeruginosa Behaviour; 4.1. Impact of NO in P. aeruginosa Gene Regulation; 4.2. Role of NO in P. aeruginosa Cell Morphology 4.3. Role of NO in P. aeruginosa Virulence4.4. Role of NO in P. aeruginosa Biofilms; 4.5. Role of NO in P. aeruginosa Membrane Vesicle Formation; 5. Clinical Relevance of NO in P. aeruginosa Infection; 5.1. Bacterial Phenotypic Switching Inside Airway Mucus; 5.2. Use of NO-Releasing Molecules; 6. Conclusions; References; Chapter Five: Emerging Roles of Nitric Oxide Synthase in Bacterial Physiology; 1. Evolutionary Significance of NOS; 2. Domain Organization and Cofactors of NOS; 3. Structural Aspects of Bacterial NOS; 3.1. How Bacterial NOS Forms a Stable Dimer; 3.2. Pterins in Bacterial NOS
• Publisher Details: Oxford, United Kingdom : Academic Press, An imprint of Elsevier
• Publication Date: 2018
• Extent: 1 online resource, illustrations
• Subjects: 572.54; Nitric oxide; Nitric-oxide synthase; SCIENCE / Life Sciences / Biochemistry; Electronic books
• Languages: English
• ISBNs: 9780128144145; 0128144149
• Related ISBNs: 9780128144138
• Notes: Note: Includes bibliographical references.; Note: Online resource; title from PDF title page (EBSCO, viewed May 23, 2018).
• Access Rights: Legal Deposit; Only available on premises controlled by the deposit library and to one user at any one time; The Legal Deposit Libraries (Non-Print Works) Regulations (UK).
• Access Usage: Restricted: Printing from this resource is governed by The Legal Deposit Libraries (Non-Print Works) Regulations (UK) and UK copyright law currently in force.