Fungal Pathogenesis : Principles and Clinical Applications /: Principles and Clinical Applications. (2001)

• Record Type: Book
• Further Information: Note: Richard Calderone.
• Authors: Calderone, Richard
• Contents: Cover; Half Title; Title Page; Copyright Page; Dedication; Contents; Preface; Introduction; Contributors; PART I. WHAT MAKES FUNGI VIRULENT?; 1 Host Recognition by Human Fungal Pathogens; I. INTRODUCTION; II. CARBOHYDRATE-PROTEIN (LECTINLIKE) BINDING SYSTEMS; A. Carbohydrate Adhesins; B. Adhesins Recognizing Host Carbohydrates; III. LIPID RECOGNITION; IV. PROTEIN·PROTEIN RECOGNITION; A. Adhesins Recognizing Serum Proteins; B. Adhesins Recognizing ECM Proteins; V . SUMMARY; ACKNOWLEDGMENTS; REFERENCES; 2 Genetic Basis of Pathogenicity in Cryptococcus neo formans; I. INTRODUCTION II. ROLE OF BIOLOGY IN C. NEOFORMANS PATHOGENESISIII. DEFINING VIRULENCE IN CRYPTOCOCCUS NEOFORMANS; IV. ROLE OF MORPHOLOGY IN PATHOGENICITY; A. Mating and Mating Type; B. Monokaryotic Fru iting; C . Switching; V. GENETIC VARIATION; VI. VIRULENCE FACTORS; A. Capsule; B. Melanin; C . Signal Transduction Homologs; D. Phospholipase; E. Mannitol; VII. ROLE OF THE HOST IMMUNE SYSTEM IN VIRULENCE; A. Race; B. Gender; C. Host Immune Status; D. Animal Models of Virulence; VIII. FUTURE RESEARCH; REFERENCES; 3 Secretory Proteins in Fungal Virulence; I. INTRODUCTION; II. PHOSPHOllPASES A. Phospholipases of Candida SpeciesB. Phospholipases of Cryptococcus Species; C. Phospholipases of Aspergillus Species; D. Role of Phospholipases in Fungal Virulence; E. Role of Fungal Extracellular Phosphollpases in Other Virulence Facilitating Functions; III. SECRETORY ASPARTIC PROTEINASES; A. Proteinases of Candida Species; B. Proteinases of Aspergillus Species; C. Role of Secretory Aspartic Proteinases in Fungal Virulence; IV. FUNGAL SECRETORY PROTEINS AS THERAPEUTIC AND DIAGNOSTIC TOOLS; A. Phospholipases; B. Secretory Aspartic Proteinases; V . CONCLUSION; ACKNOWLEDGMENTS; REFERENCES 4 Histoplasma capsulatum: Diary of an Intracellular SurvivorI. INTRODUCTION; II. RECOGNITION AND PHAGOCYTOSIS OF H. CAPSULATUM; III. STIMULATION OF THE RESPIRATORY BURST A ND PHAGOLYSOSOMAL (PL) FUSION; IV. STRATEGY FOR INTRACELLULAR SURVIVAL IN MACROPHAGES; V. MACROPHAGE ACTIVATION AND COUNTERSTRATEGIES; VI. DO NEUTROPHILS PLAYA ROLE?; VII. INTERACTION WITH DENDRITIC CELLS; VIII. CONCLUSIONS; ACKNOWLEDGMENT; REFERENCES; 5 Dimorphism in Human Pathogens; I. INTRODUCTION; II. WHAT IS DIMORPHISM? TERMINOLOGY AND STRUCTURES; III. ENVIRONMENTAL AND HOST-ADAPTED PATHOGENIC MORPHOLOGIES IV. WHY DO SOME FUNGI PRACTICE DIMORPHISM?A. Histoplasma capsulatum; B. Candida albicans; V. IMPORTANCE OF MORPHOGENESIS FOR VIRULENCE; A. Histoplasma capsulatum; B. Candida albicans; VI. REGULATION OF MORPHOGENESIS; A. Histoplasma capsulatum; B. Candida albicans; VII. MORPHOTYPE-SPECIFIC GENE EXPRESSION; A. Histoplasma capsulatum Yeast-Specific Gene Expression; B. Candida albicans Hypha-Specific Gene Expression; C. Blastomyces dermatitidis Yeast-Specific Gene Expression; VIII. SUMMARY; REFERENCES; 6 Signaling and the Biology of Human Fungal Pathogens; I. INTRODUCTION
• Publisher Details: Boca Raton, FL : CRC Press
• Publication Date: 2001
• Extent: 1 online resource
• Subjects: 616.9/69; Botany; Microbiology; Botany; Microbiology; Electronic books
• Languages: English
• ISBNs: 9781482270907; 1482270900
• Access Rights: Legal Deposit; Only available on premises controlled by the deposit library and to one user at any one time; The Legal Deposit Libraries (Non-Print Works) Regulations (UK).
• Access Usage: Restricted: Printing from this resource is governed by The Legal Deposit Libraries (Non-Print Works) Regulations (UK) and UK copyright law currently in force.