Design and analysis of animal studies in pharmaceutical development. (1998)

• Record Type: Book
• Further Information: Note: Edited by Shein-Chung Chow, Jen-pei Liu.
• Other Names: Chow, Shein-Chung, 1955-; Liu, Jen-pei, 1952-
• Contents: Experimental design principles for animal studies in pharmaceutical development; interval estimation with small samples for Median Lethal Dose (LD50) or Median Effective Dose (ED50); principles in statistical testing in randomized toxicological studies; subacute toxicity studies - proof of safety versus proof of hazard; design of long-term carcinogenicity studies; analysis of long-term carcinogenicity studies; design of reproductive studies; analysis of reproductive and development studies; the in vitro Ames tests; the in vitro Chinese hamster ovary cell mutagenesis studies.
• Publisher Details: Place of publication not identified : Chapman and Hall/CRC
• Publication Date: 1998
• Extent: 1 online resource (424 pages)
• Subjects: 615/.19; Pharmacy -- Research -- Statistical methods; Diseases -- Animal models; Laboratory animals; Préparations pharmaceutiques -- Normes de référence; Chimie pharmaceutique -- Méthodes; Modèles animaux de maladie humaine; Animaux de laboratoire; Diseases -- Animal models; Laboratory animals; Pharmacy -- Research -- Statistical methods; Médicaments -- Conception; Maladies -- Modèles animaux; Thérapeutique expérimentale; Drug Evaluation, Preclinical -- methods; Animals, Laboratory; Statistics as Topic -- methods; Toxicity Tests -- methods
• Languages: English
• ISBNs: 9781482269918; 1482269910
• Access Rights: Legal Deposit; Only available on premises controlled by the deposit library and to one user at any one time; The Legal Deposit Libraries (Non-Print Works) Regulations (UK).
• Access Usage: Restricted: Printing from this resource is governed by The Legal Deposit Libraries (Non-Print Works) Regulations (UK) and UK copyright law currently in force.