Receptor-based drug design. (1998)

• Record Type: Book
• Further Information: Note: Edited by Paul Leff.
• Other Names: Leff, Paul
• Contents: Pt. 1. Principles and measurement of drug-receptor interactions -- The characterization and classification of receptors -- Functional methods for quantifying agonists and antagonists -- Quantification of receptor interactions using binding methods -- Drug analysis based on signaling responses to G-protein-coupled receptors -- The use of electrophysiology to improve understanding of drug-receptor interactions -- pt. 2. Receptor-based drugs in medicine -- Selective adrenergic and glucocorticoid treatments for asthma -- Serotonin 5-HT₁B/D receptor agonists -- Histamine H₂-receptor antagonists -- Angiotensin antagonists -- pt. 3. Experimental and emerging drugs -- [alpha]-Adrenoceptor agonists and antagonists -- P₂U-purinoceptor angonists: emerging therapy for pulmonary diseases -- Muscarinic receptor antagonists: pharmacological and therapeutic utility -- NMDA receptor antagonists -- pt. 4. New trends in drug design -- Computational chemistry in receptor-based drug design -- Recombinant G-protein-coupled receptors as screening tools for drug discovery -- Inverse agonists and G-protein-coupled receptors.
• Publisher Details: Place of publication not identified : CRC Press
• Publication Date: 1998
• Extent: 1 online resource (400 pages)
• Subjects: 615/.19; Drug receptors; Drugs -- Design; G proteins; Ion channels; Drug Design; GTP-Binding Proteins -- physiology; Ligands; Receptors, Cell Surface -- metabolism; Receptors, Cell Surface -- physiology; Récepteurs de médicaments; Médicaments -- Conception; Protéines G; Canaux ioniques; Drug receptors; Drugs -- Design; G proteins; Ion channels; Arzneimitteldesign; Aufsatzsammlung; Receptoren; Geneesmiddelen; Ontwerpen; Arzneimitteldesign; Aufsatzsammlung; Electronic Books
• Languages: English
• ISBNs: 9781420001136; 1420001132
• Access Rights: Legal Deposit; Only available on premises controlled by the deposit library and to one user at any one time; The Legal Deposit Libraries (Non-Print Works) Regulations (UK).
• Access Usage: Restricted: Printing from this resource is governed by The Legal Deposit Libraries (Non-Print Works) Regulations (UK) and UK copyright law currently in force.