Boron-based compounds : potential and emerging applications in medicine /: potential and emerging applications in medicine. (2018)
- Record Type:
- Book
- Title:
- Boron-based compounds : potential and emerging applications in medicine /: potential and emerging applications in medicine. (2018)
- Main Title:
- Boron-based compounds : potential and emerging applications in medicine
- Further Information:
- Note: Edited by Evamarie Hey-Hawkins, Clara Viñas Teixidor.
- Editors:
- Hey-Hawkins, Evamarie, 1957-
Teixidor, Clara Viñas - Contents:
- List of Contributors vii Preface xi Part 1 Design of New Boron‐based Drugs 1 1.1 Carboranes as Hydrophobic Pharmacophores: Applications for Design of Nuclear Receptor Ligands 3; Yasuyuki Endo 1.2 Boron Cluster Modifications with Antiviral, Anticancer, and Modulation of Purinergic Receptors’ Activities Based on Nucleoside Structures 20; Anna Adamska‐Bartłomiejczyk, Katarzyna Bednarska, Magdalena Białek‐Pietras, Zofia M. Kiliańska, Adam Mieczkowski, Agnieszka B. Olejniczak, Edyta Paradowska, Mirosława Studzińska, Zofia Sułowska, Jolanta D. Żołnierczyk, and Zbigniew J. Lesnikowski 1.3 Design of Carborane‐Based Hypoxia‐Inducible Factor Inhibitors 35; Guangzhe Li, Hyun Seung Ban, and Hiroyuki Nakamura 1.4 Half‐ and Mixed‐Sandwich Transition Metal Dicarbollides and nido‐Carboranes(–1) for Medicinal Applications 60; Benedikt Schwarze, Marta Gozzi, and Evamarie Hey‐Hawkins 1.5 Ionic Boron Clusters as Superchaotropic Anions: Implications for Drug Design 109; Khaleel I. Assaf, Joanna Wilinska, and Detlef Gabel 1.6 Quantum Mechanical and Molecular Mechanical Calculations on Substituted Boron Clusters and Their Interactions with Proteins 126; Jindřich Fanfrlík, Adam Pecina, Jan Řezáč, Pavel Hobza, and Martin Lepšík Part 2 Boron Compounds in Drug Delivery and Imaging 139 2.1 Closomers: An Icosahedral Platform for Drug Delivery 141; Satish S. Jalisatgi 2.2 Cobaltabisdicarbollide‐based Synthetic Vesicles: From Biological Interaction to in vivo Imaging 159; Clara Viñas, Francesc Teixidor,List of Contributors vii Preface xi Part 1 Design of New Boron‐based Drugs 1 1.1 Carboranes as Hydrophobic Pharmacophores: Applications for Design of Nuclear Receptor Ligands 3; Yasuyuki Endo 1.2 Boron Cluster Modifications with Antiviral, Anticancer, and Modulation of Purinergic Receptors’ Activities Based on Nucleoside Structures 20; Anna Adamska‐Bartłomiejczyk, Katarzyna Bednarska, Magdalena Białek‐Pietras, Zofia M. Kiliańska, Adam Mieczkowski, Agnieszka B. Olejniczak, Edyta Paradowska, Mirosława Studzińska, Zofia Sułowska, Jolanta D. Żołnierczyk, and Zbigniew J. Lesnikowski 1.3 Design of Carborane‐Based Hypoxia‐Inducible Factor Inhibitors 35; Guangzhe Li, Hyun Seung Ban, and Hiroyuki Nakamura 1.4 Half‐ and Mixed‐Sandwich Transition Metal Dicarbollides and nido‐Carboranes(–1) for Medicinal Applications 60; Benedikt Schwarze, Marta Gozzi, and Evamarie Hey‐Hawkins 1.5 Ionic Boron Clusters as Superchaotropic Anions: Implications for Drug Design 109; Khaleel I. Assaf, Joanna Wilinska, and Detlef Gabel 1.6 Quantum Mechanical and Molecular Mechanical Calculations on Substituted Boron Clusters and Their Interactions with Proteins 126; Jindřich Fanfrlík, Adam Pecina, Jan Řezáč, Pavel Hobza, and Martin Lepšík Part 2 Boron Compounds in Drug Delivery and Imaging 139 2.1 Closomers: An Icosahedral Platform for Drug Delivery 141; Satish S. Jalisatgi 2.2 Cobaltabisdicarbollide‐based Synthetic Vesicles: From Biological Interaction to in vivo Imaging 159; Clara Viñas, Francesc Teixidor, and Adrian J. Harwood 2.3 Boronic Acid–Based Sensor for Determination of Sugars 174; Igor B. Sivaev and Vladimir I. Bregadze 2.4 Boron Compounds in Molecular Imaging 205; Bhaskar C. Das, Devi Prasan Ojha, Sasmita Das, and Todd Evans 2.5 Radiolabeling Strategies for Boron Clusters: Toward Fast Development and Efficient Assessment of BNCT Drug Candidates 232; Kiran B. Gona, Vanessa Gómez‐Vallejo, Irina Manea, Jonas Malmquist, Jacek Koziorowski, and Jordi Llop Part 3 Boron Compounds for Boron Neutron Capture Therapy 269 3.1 Twenty Years of Research on 3‐Carboranyl Thymidine Analogs (3CTAs): A Critical Perspective 271; Werner Tjarks 3.2 Recent Advances in Boron Delivery Agents for Boron Neutron Capture Therapy (BNCT) 298; Sunting Xuan and Maria da Graça H. Vicente 3.3 Carborane Derivatives of Porphyrins and Chlorins for Photodynamic and Boron Neutron Capture Therapies: Synthetic Strategies 343; Valentina A. Ol’shevskaya, Andrei V. Zaitsev, and Alexander A. Shtil 3.4 Nanostructured Boron Compounds for Boron Neutron Capture Therapy (BNCT) in Cancer Treatment 371; Shanmin Gao, Yinghuai Zhu, and Narayan Hosmane 3.5 New Boronated Compounds for an Imaging-Guided Personalized Neutron Capture Therapy 389; Nicoletta Protti, Annamaria Deagostino, Paolo Boggio, Diego Alberti, and Simonetta Geninatti Crich 3.6 Optimizing the Therapeutic Efficacy of Boron Neutron Capture Therapy (BNCT) for Different Pathologies: Research in Animal Models Employing Different Boron Compounds and Administration Strategies 416; Amanda E. Schwint, Andrea Monti Hughes, Marcela A. Garabalino, Emiliano C.C. Pozzi, Elisa M. Heber, and Veronica A. Trivillin Index … (more)
- Edition:
- 1st
- Publisher Details:
- Hoboken, New Jersey : John Wiley & Sons, Inc
- Publication Date:
- 2018
- Extent:
- 1 online resource
- Subjects:
- 615.2671
Boron compounds
Boron compounds -- Diagnostic use
Boron compounds -- Therapeutic use - Languages:
- English
- ISBNs:
- 9781119275596
- Related ISBNs:
- 9781119275589
- Notes:
- Note: Description based on CIP data; resource not viewed.
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- Legal Deposit; Only available on premises controlled by the deposit library and to one user at any one time; The Legal Deposit Libraries (Non-Print Works) Regulations (UK).
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- Physical Locations:
- British Library HMNTS - ELD.DS.276846
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- 02_326.xml