The Ras superfamily of GTPases. (2018)

• Record Type: Book
• Further Information: Note: [edited by] Juan Carlos Lacal, Frank McCormick.
• Editors: Lacal, Juan Carlos; McCormick, Frank, 1950-
• Contents: Cover; Half Title; Title Page; Copyright Page; PREFACE; TABLE OF CONTENTS; I: THE WORLD OF ras GENES AND THEIR PRODUCTS; Oncogenic Potential of ras Genes; Chapter 1 ras Genes Involvement in Carcinogenesis: Lessons from Animal Model Systems; Structure and Properties of ras Proteins; Chapter 2 Three-Dimensional Structure of p2l and Its Implications; Chapter 3 Posttranslational Processing of ras and ms-Related Proteins; Chapter 4 Biological Activities of ras Genes; Chapter 5 p2l-ras and Receptor Signaling; Chapter 6 ras-p21 Proteins: Switch Devices for Signal Transduction Genetic Approaches to ras FunctionChapter 7 The RAS System in Yeasts; Chapter 8 Regulation and Function of Two Developmentally Regulated ras Genes in Dictyostelium; Chapter 9 ras Genes in Drosophila melanogaster; II: THE ras SUPERFAM; General Overview; Chapter 10 ras Homologs: A Comparison of Primary Structures; The ras Branch; Chapter 11 Krev-1 and the Related Genes; Chapter 12 ral Gene Products and Their Regulation; The rho Branch; Chapter 13 The rho Gene Family; Chapter 14 rac Gene Products Chapter 15 CDC42: A Member of the ras Superfamily Involved in the Control of Cellular Polarity during the Saccharomyces cerevisiae Cell CycleChapter 16 CDC42Hs: The Human Homolog of a Yeast Cell-Division Cycle Protein; Chapter 17 Identification of Novel ras Family Genes in a Human Teratocarcinoma Cell Line by Oligonucleotide Screening; The rab Branch; Chapter 18 The rab Gene Family; Chapter 19 The YPT Protein Family in Yeast; Chapter 20 The SAS Genes: Functionally Distinct Members of the YPT1/SEC4 Family in Dictyostelium; III: FUNCTIONAL REGULATION OF ras AND ras-RELATED GTPases GAPs and Related FactorsChapter 21 Regulators and Effectors of ras Proteins; Chapter 22 Properties of GAP Proteins; Chapter 23 The IRA Gene Family in Yeast; Chapter 24 GAPs Specific for the rapl/Krev-1 Protein; Exchange Factors for ras and ras-Related Proteins; Chapter 25 Exchange Factors; Chapter 26 Properties of CDC25-Like Proteins; Chapter 27 GDP/GTP Exchange Proteins for Small GTP-Binding Proteins; Index
• Publisher Details: Boca Raton, FL : CRC Press
• Publication Date: 2018
• Copyright Date: 1993
• Extent: 1 online resource, illustrations (some color)
• Subjects: 616.99/407/1; Ras oncogenes; Guanosine triphosphatase; Guanosine triphosphatase genes; Ras proteins; GTPase-activating protein; Cell transformation; Cell Biology; Molecular Biology; Oncology; BIOSCIENCEnetBASE; SCI-TECHnetBASE; LIFESCIENCEnetBASE; MEDICINEnetBASE; STMnetBASE; HEALTH & FITNESS / Diseases / General; MEDICAL / Clinical Medicine; MEDICAL / Diseases; MEDICAL / Evidence-Based Medicine; MEDICAL / Internal Medicine; Electronic books
• Languages: English
• ISBNs: 9780203709931; 0203709934; 9781351356855; 1351356852; 9781351356848; 1351356844
• Related ISBNs: 1138105120; 9781138105126; 9781138562301
• Notes: Note: Includes bibliographical references and index.
• Access Rights: Legal Deposit; Only available on premises controlled by the deposit library and to one user at any one time; The Legal Deposit Libraries (Non-Print Works) Regulations (UK).
• Access Usage: Restricted: Printing from this resource is governed by The Legal Deposit Libraries (Non-Print Works) Regulations (UK) and UK copyright law currently in force.