Sulfatases Of Microbial Origin. Volume II (2018)

• Record Type: Book
• Further Information: Note: Kenneth S. Dodgson, Graham F. White, John W. Fitzgerald.
• Other Names: Dodgson, Kenneth S (Kenneth Scott), 1922-; White, Graham F (Graham Francis), 1947-; Fitzgerald, John W (John Walter), 1938-
• Contents: Cover; Title Page; Copyright Page; PREFACE; THE AUTHORS; Table of Contents; Chapter 1: Hydrolysis of Phosphosulfates, Sulfamides, and Glucosinolates; I. Introduction; II. Hydrolysis of Phosphosulfate Linkages; A. Active Sulfates; B. Degradation of APS and PAPS by Mammalian Enzymes; C. Microbial Degradation of APS and PAPS; 1. Active Sulfate Degradation in Unicellular Algae and the Cyanobacteria; 2. Active Sulfate Degradation in Bacteria; 3. Active Sulfate Degradation in Fungi; D. Concluding Remarks; III. Hydrolysis of Sulfamide Linkages; A. Introduction B. The Sulfamidase of Pseudomonassp. Strain KC. Induction of the Enzyme; D. Concluding Remarks; IV. Hydrolysis of Hydroxylamine O-Sulfate (Glucosinolate) Linkages; A. Glucosinolate Substrates (Mustard Oil Glycosides); B. ""Myrosinase"" Enzymes; References; Chapter 2: Mechanisms of Enzymic and Nonenzymic Hydrolysis of Sulfate Esters; I. Introduction; II. Arylsulfatases; A. Substrate Binding; 1. Dependence on pH and Substitution in the Aryl Nucleus; 2. Hydrophobic Interactions; B. Mechanism of Hydrolysis of the Enzyme-Substrate Complexes 1. Comparison of Enzymic and Nonenzymic Hydrolyses of Aryl Sulfate Esters2. Tyramine Effects; 3. Position of Bond Cleavage; 4. Inhibition by Sulfate; 5. Functional Groups at the Active Site; III. Alkylsulfatases; A. Substrate Binding; 1. Primary Alkylsulfatase; 2. Secondary Alkylsulfatases; 3. The Nature of the Hydrophobic Interactions; B. Mechanism of Hydrolysis of the Enzyme-Substrate Complexes; 1. Effect of Alkyl Chain Length; 2. Position of Bond Cleavage; 3. Nonenzymic Hydrolysis of Alkyl Sulfate Esters; 4. The Significance of Substitution at the Esterified Carbon Atom IV. Choline SulfataseA. Substrate Binding; B. Mechanism of Hydrolysis of the Enzyme-Substrate Complex; V. Adenosine 5'-Phosphosulfate Sulfatase; A. Substrate Binding; B. Mechanism of Hydrolysis of the Enzyme-Substrate Complex; 1. Position of Bond Cleavage; 2. Nonenzymic Hydrolysis; VI. Sulfamidase; VII. Concluding Remarks; References; Chapter 3: Physiological and Genetic Control of Sulfatase Formation and Sulfate Ester Transport; I. Introduction; II. Inducible Sulfatases; A. General Comments; B. The Inducible Alkylsulfatases; 1. Inducer Specificity 2. Catabolite Repression of Primary Alkylsulfatase Induction in Pseudomonas aeruginosa3. Adenylate Energy Charge as a Regulator of Alkylsulfatase Induction in P. aeruginosa; 4. Influence of Divalent Cations; 5. Catabolite Repression of Inducible Alkylsulfatases in Pseudomonas C12B; 6. Environmental Significance of Control by Exogenous Nucleotides; III. Derepressible Sulfatases; A. General Comments; B. Nature of Metabolite Repressers and Derepressors: Centralized Control by Inorganic Sulfate; C. Environmental Significance; D. Possibility of Partial Regulation by Adenylate Energy Charge
• Publisher Details: Boca Raton, FL : CRC Press
• Publication Date: 2018
• Extent: 1 online resource (208 p.)
• Subjects: 572.7; Sulfatases; Microbial enzymes; SCIENCE / Life Sciences / Biochemistry; Electronic books; Electronic books
• Languages: English
• ISBNs: 9781351093903; 1351093908; 9781351085458
• Related ISBNs: 135108545X; 9781315897905
• Notes: Note: Includes bibliographical references and index.
• Access Rights: Legal Deposit; Only available on premises controlled by the deposit library and to one user at any one time; The Legal Deposit Libraries (Non-Print Works) Regulations (UK).
• Access Usage: Restricted: Printing from this resource is governed by The Legal Deposit Libraries (Non-Print Works) Regulations (UK) and UK copyright law currently in force.