Myopathies. (2014)

• Record Type: Book
• Other Names: Dimachkie, Mazen
• Contents: Front Cover; Myopathies; Copyright; Contributors; Contents; Neurologic Clinics; Preface; A Pattern Recognition Approach to Patients with a Suspected Myopathy; Key points; Introduction; Clinical evaluation; Which Negative and/or Positive Symptoms Do Patients Demonstrate?; What is the Temporal Evolution?; Is There a Family History of a Myopathic Disorder?; Are There Precipitating Factors That Trigger Episodic Weakness or Stiffness?; Are There Associated Systemic Symptoms or Signs?; What is the Distribution of Weakness?; Pattern recognition approach to myopathic disorders. Pattern 1: Proximal Limb-Girdle WeaknessPattern 2: Distal Weakness; Pattern 3: Proximal Arm/Distal Leg Weakness (Scapuloperoneal); Pattern 4: Distal Arm/Proximal Leg Weakness; 68-year old with slowly progressive muscle weakness; Comment; Pattern 5: Ptosis with or Without Ophthalmoparesis; 70-year old with progressive dysphagia and weakness; Comment; Pattern 6: Prominent Neck Extensor Weakness; Pattern 7: Bulbar Weakness; Pattern 8: Episodic Pain, Weakness, and Myoglobinuria; Pattern 9: Episodic Weakness Delayed or Unrelated to Exercise; Pattern 10: Stiffness and Decreased Ability to Relax. Laboratory approach in the evaluation of a suspected myopathyCK; Electrophysiologic Studies; The Muscle Biopsy; Molecular Genetic Studies; Other Tests; Summary; Web sites; References; Idiopathic Inflammatory Myopathies; Key points; Epidemiology; Clinical presentation; Dermatomyositis; Polymyositis; Necrotizing Myopathy; Conditions associated with dermatomyositis, polymyositis, and necrotizing myopathy; Polyarthritis; Interstitial Lung Disease; Malignancy; Autoimmune Necrotizing Myopathy; Cardiac Defects; Laboratory studies in dermatomyositis, polymyositis, and necrotizing myopathy. Cancer ScreeningPulmonary Function Testing; Biomarker Monitoring; Antibody Identification; Electrophysiology of dermatomyositis, polymyositis, and necrotizing myopathy; Muscle imaging; Muscle histopathology and pathogenesis of DM, PM, and NM; Dermatomyositis; Polymyositis; Necrotizing Myopathy; Therapy for dermatomyositis, polymyositis, and necrotizing myopathy; Corticosteroids; Methotrexate; Azathioprine; Intravenous Immunoglobulin; Treatment of Refractory Patients; IIM Associated with ILD; Promising Therapies; Physical Therapy; Prognosis; References; Inclusion Body Myositis; Key points. EpidemiologyClinical Presentation; Associated Conditions; Laboratory and Electrophysiologic Testing; Muscle Imaging; Muscle Histopathology; Pathogenesis; Diagnostic and research criteria; ENMC 2000; MRC 2010; ENMC 2011; Therapy; Ongoing Research; Prognosis; Exercise; Summary; References; Toxic Myopathies; Key points; Introduction; Pathophysiology/Pathogenesis; Necrotizing myopathy; Introduction; Statins; Clinical presentation; Laboratory features and electrophysiology; Histopathology; Pathogenesis; Treatment; Cholesterol-Lowering Drugs (Excluding Statins); Immunophilins; Clinical features.
• Publisher Details: Philadelphia : Elsevier
• Publication Date: 2014
• Extent: 1 online resource (305 pages)
• Subjects: 616.80442; Medicine; Molecular neurobiology; Nervous system -- Diseases -- Genetic aspects; Neurogenetics; HEALTH & FITNESS -- Diseases -- General; MEDICAL -- Clinical Medicine; MEDICAL -- Diseases; MEDICAL -- Evidence-Based Medicine; MEDICAL -- Internal Medicine; Medicine; Molecular neurobiology; Nervous system -- Diseases -- Genetic aspects; Neurogenetics; Electronic books
• Languages: English
• ISBNs: 9780323320382; 0323320384
• Related ISBNs: 9780323320191; 0323320198
• Notes: Note: Print version record.
• Access Rights: Legal Deposit; Only available on premises controlled by the deposit library and to one user at any one time; The Legal Deposit Libraries (Non-Print Works) Regulations (UK).
• Access Usage: Restricted: Printing from this resource is governed by The Legal Deposit Libraries (Non-Print Works) Regulations (UK) and UK copyright law currently in force.