Automated hematology analyzers : state of the art /: state of the art. ([2015])

• Record Type: Book
• Further Information: Note: Editors, Carlo Brugnara, Alexander Kratz.
• Editors: Brugnara, Carlo; Kratz, Alexander
• Contents: Front Cover; Automated Hematology Analyzers:State ofthe Art; Copyright; Contributors; Contents; Clinics In Laboratory Medicine; Preface; Development, History, and Future of Automated Cell Counters; Key points; Introduction; Utility of a blood count; History and current methods; Manual Counting Methods; Automated Counting Methods; Methods based on optical measurements; Methods based on electrical measurements; Novel methods under development; New Contrast Agents and Methods; The Need for Portability; Miniaturization of flow-based cytometers; The resurgence of image-based blood counters. In-vivo Automated Blood CountFuture; References; White Blood Cell Counts; Key points; Introduction; The white blood cell count; Methods; Automation of the Differential; Electrical Impedance; Radiofrequency Conductivity; Light Scattering; Cytochemistry; Fluorescent Labeling; Monoclonal Antibodies; Automated Differential Cell Counters; Automated Sampling Modes; Sources of error; Reporting and flagging; White blood cell parameters; Nucleated Red Blood Cells; Large Unstained Cells; Hematopoietic Progenitor Cells; Immature Granulocytes; Granularity Index; Lymph Index; Summary; References. Analysis of Bone Marrow Aspiration Fluid Using Automated Blood Cell CountersKey points; Introduction; Bone Marrow Fluid; Analytical Technologies in Automated Blood Cell Counters; Usefulness of Automated Analysis of Bone Marrow Aspirates; Difficulties in cell counting in bone marrow fluid; Erythroblasts and Other Immature Cells; Large Cells, Cell Particles, and Clusters; Lipid Droplets; Impossibility to Store Anticoagulated Specimen; Technical issues: should bone marrow fluid be pretreated?; Anticoagulation; Dilution; Filtration; Washing; Homogenization and Disaggregation. Results of published studiesNucleated Cell Count as an Indicator of Bone Marrow Cellularity; Differential Bone Marrow Cell Count-Comparison with Microscope; Bone Marrow Blasts: Automated Count, Sensitivity, and Specificity; Scattergrams and distribution patterns: qualitative information; Bone marrow and peripheral blood; Bone Marrow Fluid as a Substitute of Peripheral Blood for Laboratory Tests; Reticulocytes in Bone Marrow and Peripheral Blood; Animal hematology: a breakthrough in the automated marrow analysis; Summary; References; Red Blood Cell Population Dynamics; Key points; Introduction. Quantifying Red Cell Dynamics Would Complement the Static Complete Blood CountReticulocyte Counts Provide a Glimpse of Value of Red Cell Dynamics; Estimating Red Cell Maturation and Clearance Rates Requires Modeling; Basic scientific studies show aspects of red blood cell population dynamics; Empirical Studies of In Vivo Volume Dynamics; Initial volume changes are fast; Subsequent volume changes are slow; Empirical Studies of In Vivo Hemoglobin Content Dynamics; Initial hemoglobin changes are more significant; Subsequent hemoglobin changes are less pronounced.
• Publisher Details: Philadelphia, Pennsylvania : Elsevier
• Publication Date: 2015
• Copyright Date: 2015
• Extent: 1 online resource (viv, 224 pages), illustrations (some color)
• Subjects: 612.11; Blood -- Analysis; Blood cell count -- Equipment and supplies; MEDICAL -- Physiology; SCIENCE -- Life Sciences -- Human Anatomy & Physiology; Blood -- Analysis; Blood cell count -- Equipment and supplies; Electronic books
• Languages: English
• ISBNs: 0323356818; 9780323356817
• Notes: Note: Includes bibliographical references.; Note: Online resource; title from PDF title page (EBSCO, viewed February 24, 2016).
• Access Rights: Legal Deposit; Only available on premises controlled by the deposit library and to one user at any one time; The Legal Deposit Libraries (Non-Print Works) Regulations (UK).
• Access Usage: Restricted: Printing from this resource is governed by The Legal Deposit Libraries (Non-Print Works) Regulations (UK) and UK copyright law currently in force.