Prostate cancer. (2013)

• Record Type: Book
• Further Information: Note: Editor, Christopher J. Sweeney ; consulting editors, George P. Canellos, H. Franklin Bunn.
• Editors: Sweeney, Christopher J
• Contents: Front Cover; Prostate Cancer; Copyright; Contributors; Contents; Forthcoming Issues; Preface; Early Detection, PSA Screening, and Management of Overdiagnosis; Key points; Introduction; PSA screening; Randomized controlled trials of PSA screening; PSA screening modifications to improve detection; PSA refinements; PSA Velocity; Free PSA; Complexed PSA; PSA Density; Risk-based screening; Prediction tools; Novel screening tests; PCA3; Prostate Health Index; TMPRSS2:ERG Gene Fusion; Current screening guidelines; Overdiagnosis in prostate cancer; Impact of overdiagnosis. Watchful waiting and observationActive surveillance; Summary; References; Surgical Management of Prostate Cancer; Key points; Introduction; Patient selection; Surgical technique; Cavernosal nerve sparing; Pelvic lymph node dissection; Surgical margins; Low-risk prostate cancer; Definition of Low-Risk Prostate Cancer; Outcomes for Low-Risk Disease Following Radical Prostatectomy; High-risk prostate cancer; Definition of High-Risk Prostate Cancer; Outcomes for High-Risk Disease Following Radical Prostatectomy; Neoadjuvant therapy before radical prostatectomy. Is radical prostatectomy the preferred treatment for high-risk prostate cancer?Alternative Surgical Therapies; Summary; References; Contemporary Issues in Radiotherapy for Clinically Localized Prostate Cancer; Key points; Introduction; Principles of radiation therapy; Patient selection for radiation therapy with curative intent; Risk Stratification; Assessment, Comorbidities, and Contraindications; Defining the radiation target; Prostate and Seminal Vesicles; Whole Pelvic Irradiation; External Beam Radiotherapy; IMRT; Image-Guided Radiation Therapy; Dose-Escalated Radiotherapy; Toxicity. Role of Androgen Deprivation TherapyBrachytherapy; LDR Brachytherapy; Patient selection for brachytherapy; Outcomes; Toxicity; HDR Brachytherapy; Toxicity; Postprostatectomy radiotherapy; PPRT Volume Delineation; Adjuvant Therapy; Salvage Therapy; PPRT Toxicity (Adjuvant and Salvage); Ongoing Trials; Second malignancy risks from radiotherapy; Future directions in prostate radiotherapy; Anatomic and Molecular Imaging; Hypofractionation; Stereotactic Body Radiotherapy; New Endocrine Therapies; Summary; References; Imaging in Prostate Carcinoma; Key points; Introduction. Imaging modalities commonly used to evaluate prostate cancerTRUS; MRI; CT; Skeletal Scintigraphy (99mTc-MDP Bone Scan); PET; Imaging in staging and management of prostate cancer: localized and metastatic disease; Future directions; DCE-MRI; MRSI; DWI; mpMRI; PET; Summary; References; Neoadjuvant and Adjuvant Hormonal and Chemotherapy for Prostate Cancer; Key points; Introduction; Adjuvant hormone therapy following prostatectomy; Adjuvant RT following prostatectomy; Adjuvant androgen deprivation therapy in combination with RT; Adjuvant chemotherapy.
• Publisher Details: Philadelphia : Elsevier
• Publication Date: 2013
• Extent: 1 online resource (xii, pages 1092-1295), illustrations
• Subjects: 616.99463; Prostate -- Cancer; Prostatic Neoplasms; HEALTH & FITNESS -- Diseases -- General; MEDICAL -- Clinical Medicine; MEDICAL -- Diseases; MEDICAL -- Evidence-Based Medicine; MEDICAL -- Internal Medicine; Prostate -- Cancer; Electronic books
• Languages: English
• ISBNs: 9780323227230; 0323227236; 1336247118; 9781336247116
• Related ISBNs: 9780323227223; 0323227228
• Notes: Note: Includes bibliographical references and index.; Note: Print version record.
• Access Rights: Legal Deposit; Only available on premises controlled by the deposit library and to one user at any one time; The Legal Deposit Libraries (Non-Print Works) Regulations (UK).
• Access Usage: Restricted: Printing from this resource is governed by The Legal Deposit Libraries (Non-Print Works) Regulations (UK) and UK copyright law currently in force.