Systemic lupus erythematosus : a companion to Rheumatology /: a companion to Rheumatology. (©2007)

• Record Type: Book
• Uniform Title: Rheumatology.
• Further Information: Note: [edited by] George Tsokos, Caroline Gordon, Josef Smolen.
• Other Names: Tsokos, George C; Gordon, Caroline, 1956-; Smolen, Josef S, 1950-
• Contents: Epidemiology and Diagnosis -- -- 1. Epidemiology -- 2. Disease Activity Measures -- 3. Disease Outcome -- 4. Quality of Life and Economic Aspects -- Pathogenesis -- 1. Overview of the Pathogenesis of SLE -- 2. Genetics -- 3. Hormones -- 4. Immunoregulation ₆ T Cells, B cells, and cytokines. -- 5. Cell Surface Receptors ostimulation/BAFF/FcgR/TLRs) -- 6. Dendritic Cells -- 7. Apoptosis -- 8. Structure and Origin of Autoantibodies -- 9. Animal Models -- 10. Genetics of murine lupus -- 11. Infection and autoimmunity -- Mechanisms of Tissue Damage -- 1. Complement -- 2. Immune complexes -- 3. Antibodies -- a. ANA and standardization of antibody techniques -- b. Anti-DNA -- c. Anti-splicesomosal ab -- d. Anti-Ro/La -- e. Anti-Histone -- f. APL -- g. Anti-neuronal -- 4. PMNs -- 5. Mechanisms of renal damage -- 6. Mechanisms of vascular damage -- 7. Nitric Oxide -- Clinical Aspects of the Disease -- 1. Constitutional Symptoms and Fatigue -- 2. Skin -- 3. Kidney -- 4. Heart -- 5. Lung -- 6. GI/liver/pancreas -- 7. Infections -- 8. Blood (anti-phospholipid syndrome) -- 9. Nervous System -- 10. Overlap Syndromes -- 11. Ophthalmic Manifestations -- 12. Pregnancy -- 13. Fertility -- 14. Neo-natal lupus -- 15. Hereditary and Malignant Lupus-like Diseases -- Treatment of the Disease -- 1. Non-Steroidals ₆ Anti-Malarials and Statins -- 2. Steroid Treatment -- 3. Cytotoxic Drug Treatment including M.M.F -- 4. PAPS -- 5. New Treatments.
• Publisher Details: Philadelphia : Mosby Elsevier
• Publication Date: 2007
• Copyright Date: 2007
• Extent: 1 online resource (xv, 586 pages), illustrations (some color)
• Subjects: 616.7/7; Systemic lupus erythematosus; Lupus Erythematosus, Systemic; HEALTH & FITNESS -- Diseases -- Musculoskeletal; MEDICAL -- Orthopedics; MEDICAL -- Rheumatology; Lupus érythémateux disséminé; Systemic lupus erythematosus; Lupus érythémateux aigu disséminé; Electronic books
• Languages: English
• ISBNs: 9780323070874; 0323070876
• Related ISBNs: 9780323044349; 0323044344
• Notes: Note: Includes bibliographical references and index.; Note: Print version record.
• Access Rights: Legal Deposit; Only available on premises controlled by the deposit library and to one user at any one time; The Legal Deposit Libraries (Non-Print Works) Regulations (UK).
• Access Usage: Restricted: Printing from this resource is governed by The Legal Deposit Libraries (Non-Print Works) Regulations (UK) and UK copyright law currently in force.