Otolaryngologic clinics of North America. Oral cavity and oropharyngeal cancer / August 2013, Volume 46, Number 4, ([2013])

• Record Type: Book
• Other Titles: Oral cavity and oropharyngeal cancer
• Further Information: Note: Editor, Jeffrey N. Myers, Erich M. Sturgis.
• Editors: Myers, Jeffrey (Jeffrey N.); Sturgis, Erich M
• Contents: Cover image; Title page; Table of Contents; Contributors; Editors; Authors; Forthcoming Issues; Forthcoming Issues; Recent Issues; A Tale of Two Cancers: Carcinomas of the Oral Cavity and Oropharynx; Key points; Introduction; Overview of oral cavity and oropharyngeal cancer; Summary; Etiology and Biology; Epidemiology of Oral-Cavity and Oropharyngeal Carcinomas; Key points; Evolution of the tobacco epidemic; Emergence of the HPV-associated cancer epidemic; HPV vaccination; Future burdens of oral-cavity and oropharyngeal cancer. Impact of Human Papillomavirus on Oropharyngeal Cancer Biology and Response to TherapyKey points; Introduction; HPV basics; Clinical implications of HPV-positive OPSCC; Implications of HPV for treatment and outcomes; Summary; Oral Cavity and Oropharyngeal Squamous Cell Carcinoma Genomics; Key points; Introduction; Genetic alterations; Epigenetic alterations; Altered gene expression profiles; Implications for therapy; Future goals for genomics studies; Summary; Why Otolaryngologists Need to be Aware of Fanconi Anemia; Key points; Introduction to Fanconi anemia; Solid tumors in patients with FA. Therapeutic options in FAClinical outcomes/complications/concerns in FA; Summary; Evaluation and Therapy; Oral Premalignancy; Key points; Introduction; Primary, secondary, and tertiary prevention for oral squamous cell carcinoma; Natural history and treatment of oral leukoplakia, the most frequent premalignancy disease; Clinical, pathologic, and molecular markers for risk assessment; Chemoprevention: rationale and results; Retinoids; Cyclooxygenase inhibitors; Green tea polyphenols; p53-targeted agents; Thiazolidinediones; EGFR inhibitors; Summary. Evaluation and Staging of Squamous Cell Carcinoma of the Oral Cavity and OropharynxKey points; Introduction; Diagnosis and evaluation of SCCOC; Diagnosis and evaluation of SCCOP; Prognostic staging for SCCOC; Prognostic staging for SCCOP; Novel approaches in evaluation and staging; Surgical Innovations; Key points; Introduction; Traditional surgical approaches; Neck dissection and SLNB for oral cavity SCC; Surgical innovations in oropharyngeal cancer; Summary; Advances in Radiation Oncology for the Management of Oropharyngeal Tumors; Key points; RT fractionation; Chemoradiation. Epidermal growth factor receptor inhibition and RTRT as monotherapy for early T-category oropharyngeal cancer; RT for unknown primary metastatic to cervical lymph nodes; IMRT for oropharyngeal carcinoma; Intensity-modulated proton therapy for oropharyngeal carcinoma; Other areas of active investigation; The Role of Systemic Treatment Before, During, and After Definitive Treatment; Key points; Introduction; Concurrent chemoradiation therapy; Radiation with concurrent cetuximab; Induction chemotherapy; Adjuvant concurrent chemoradiation therapy; Summary; Quality of Life and Quality of Care.
• Publisher Details: Philadelphia, Pennsylvania : Elsevier
• Publication Date: 2013
• Extent: 1 online resource (516 pages)
• Subjects: 616.99/431; Mouth -- Cancer; Pharynx -- Cancer; HEALTH & FITNESS -- Diseases -- General; MEDICAL -- Clinical Medicine; MEDICAL -- Diseases; MEDICAL -- Evidence-Based Medicine; MEDICAL -- Internal Medicine; Mouth -- Cancer; Pharynx -- Cancer; Cancer; Mouth -- Cancer; Pharynx -- Cancer; Electronic books
• Languages: English
• ISBNs: 9780323186322; 0323186327
• Notes: Note: Includes bibliographical references.; Note: Description based on online resource; title from digital title page (viewed on July 22, 2016).
• Access Rights: Legal Deposit; Only available on premises controlled by the deposit library and to one user at any one time; The Legal Deposit Libraries (Non-Print Works) Regulations (UK).
• Access Usage: Restricted: Printing from this resource is governed by The Legal Deposit Libraries (Non-Print Works) Regulations (UK) and UK copyright law currently in force.