Dyneins : dynein mechanics, dysfunction, and disease /: dynein mechanics, dysfunction, and disease. (2017)

• Record Type: Book
• Further Information: Note: Edited by Stephen M. King.
• Editors: King, Stephen M
• Contents: I. Structure and Mechanics of Dynein Motors Electron microscopy of isolated dynein complexes and the power stroke mechanism (Oiwa, Sakakibara and Furuta) Mechanism and regulation of dynein motors (Schmidt and Carter) Structural analysis of dynein intermediate and light chains (Williams, Siglin, Lightcap and Dawn) Biochemical purification of axonemal and cytoplasmic dyneins (Inaba) Single molecule dynein motor mechanics in vitro (Yildiz) Biophysical properties of dynein in vivo (Shubeita, Reddy and Gross) Mechanics of bidirectional cargo transport. (Hancock) Chemical probes for dynein (Steinman and Kapoor) Computational modeling of dynein activity and the generation of flagellar beating waveforms (Geyer, Sartori, Jülicher and Howard) II. Dynein Dysfunction and Disease Impacts of virus-mediated manipulation of host dynein (Milev, Yao, Berthoux and Mouland) Use of mouse genetics to probe cytoplasmic dynein function (Terenzio, Koley, Fisher and Fainzilber) Cytoplasmic dynein and its regulators in neocortical development and disease (Doobin and Vallee) Cytoplasmic dynein dysfunction and neurodegenerative disease (Moughamian and Holzbaur) Dynein dysfunction as a cause of primary ciliary dyskinesia and other ciliopathies (Loges and Omran) Severe skeletal abnormalities caused by defects in retrograde intraflagellar transport dyneins (Schmidts and Mitchison) Ciliary dynein dysfunction as a consequence of chronic alcohol exposure. (Price, Yang, Sisson and Wirschell) Dynein-based motility of pathogenic protozoa (Imhof and Hill) Dynein axonemal light chain 4: involvement in congenital mirror movement disorder (Vincent) Does dynein influence the non-Mendelian inheritance of chromosome 17 homologues in male mice? (Pilder)
• Edition: Second edition
• Publisher Details: Amsterdam : Academic Press
• Publication Date: 2017
• Extent: 1 online resource
• Subjects: 572.6; Dynein; Cytoskeletal proteins
• Languages: English
• ISBNs: 9780128097014
• Related ISBNs: 9780128094709
• Notes: Note: Description based on CIP data; resource not viewed.
• Access Rights: Legal Deposit; Only available on premises controlled by the deposit library and to one user at any one time; The Legal Deposit Libraries (Non-Print Works) Regulations (UK).
• Access Usage: Restricted: Printing from this resource is governed by The Legal Deposit Libraries (Non-Print Works) Regulations (UK) and UK copyright law currently in force.