Measurement and analysis of kinetic isotope effects. (2017)

• Record Type: Book
• Further Information: Note: Volume editor, Michael E. Harris, Vernon Anderson.
• Editors: Harris, Michael E; Anderson, Vernon
• Contents: Measurement of enzyme binding isotope effects; Vern Schramm Chemical ligation and isotope labeling to locate dynamic effects; Rudolf Alleman Measurement of heavy enzyme isotope effects; Amnon Kohen Extracting kinetic isotope effects from a global analysis of reaction progress curves; Sam Hay KIE of metabolic flux and enzymes; Guillaume Tcherkez Solvent and Primary KIE on Flavin Enzymes; Paul Fitzpatrick The Rapid Determination of Primary Deuterium Isotope Effects on Enzyme-Catalyzed Proton Transfer at Carbon in 50/50 HOH/DOD; John Richard 18-O isotope effects on oxygenases; Judith Klinman Chlorine isotope effects on dehalogenases; Piotr Paneth Chlorine isotope effects (w/Paneth); Agnieszka Dybala-Defratyka Kinetic Deuterium Isotope Effects in Cytochrome P450 Reactions; F. Peter Guengerich Use of Isotopes and Isotope Effects for Investigations of Diiron Oxygenase Mechanisms; John Lipscomb Characterization of substrate, co-substrate, and product isotope effects associated with enzymatic oxygenations using gas- and liquid chromatography/isotope ratio mass spectrometry; Thomas Hofstetter NMR titrations to determine equilibrium isotope effects; Charles Perrin NMR to characterize the nonstatistical distribution of stable isotopes in metabolism; Richard Robins Applications of isotope ratio mass spectrometry in sports drug testing: accounting for isotope fractionation in analysis of biological samples; Thomas Piper Whole molecule mass spectrometry to measure KIEs on RNA 2’O-transphosphorylation reactions; Mike Harris Isotope Effects on the Concentration of Steady State Intermediates; Hung-Wen Liu and Mark Ruszczycky Headspace analysis of CO2 to measure carbon kinetic isotope effects in decarboxylation reactions; Ron Kluger 32P/33P remote label methods to measure RNA kinetic isotope effects; Joseph Piccirilli Isotope effects and MS analysis of pseudouridine synthase enzymes; Eugene Mueller Nucleophile isotope effects on glycosyl transfer reactions; Andrew James Bennet
• Publisher Details: Amsterdam : Academic Press
• Publication Date: 2017
• Extent: 1 online resource
• Subjects: 572.7; Enzyme kinetics; Enzymology
• Languages: English
• ISBNs: 9780128122747
• Related ISBNs: 9780128122730
• Notes: Note: Description based on CIP data; resource not viewed.
• Access Rights: Legal Deposit; Only available on premises controlled by the deposit library and to one user at any one time; The Legal Deposit Libraries (Non-Print Works) Regulations (UK).
• Access Usage: Restricted: Printing from this resource is governed by The Legal Deposit Libraries (Non-Print Works) Regulations (UK) and UK copyright law currently in force.