Neurobiology of TRP Channels. (2017)

• Record Type: Book
• Further Information: Note: Tamara Luti Rosenbaum Emir.
• Authors: Rosenbaum Emir, Tamara Luti
• Contents: Cover; Half Title; Series Page; Title page; Copyright Page; Dedication Page; Table of Contents; Preface; Editor; List of Contributors; Chapter 1: TRP Channels ; 1.1 Introduction; 1.2 TRPA; 1.3 TRPC; 1.4 TRPM; 1.5 TRPML; 1.6 TRPN; 1.7 TRPP; 1.8 TRPV; 1.9 Conclusion; References; Chapter 2: Molecular Mechanisms of Temperature Gating in TRP Channels; 2.1 Introduction; 2.2 Structural Prelude; 2.3 Ligand and Voltage Gating in ThermoTRP Channels; 2.4 Mechanism of Gating by Temperature; 2.5 Physical Theories of Activation by Temperature; 2.5.1 Role of Pore Region; 2.5.2 Role of Transmembrane Domains 2.5.3 Role of Intracellular RegionsAcknowledgments; References; Chapter 3: TRP Channels in Vision; 3.1 Introduction; 3.2 Drosophila Phototransduction; 3.2.1 Coupling of Photoexcited Rhodopsin to Inositol Phospholipid Hydrolysis; 3.2.2 Rhodopsin and the Photochemical Cycle; 3.2.3 Photoreceptor Potential and Prolonged Depolarizing Afterpotential: A Tool for Discovery of Phototransduction Components; 3.2.4 Light-Activated G Protein; 3.2.5 Role of PLC in Light Excitation and Adaptation; 3.2.6 Phosphoinositide (PI) Cycle; 3.2.7 Single-Photon Responses and Spontaneous Dark Bumps 3.2.7.1 Spontaneous Dark Bumps3.2.8 Single-Photon Responses: Quantum Bumps; 3.3 Evolution of TRPC Channels in Photoreceptor Cells; 3.3.1 Complex Phylogeny of TRPC Channels in Invertebrate Species; 3.3.2 TRPC Channels from Two Major Clades Shown to Be Expressed in Microvillar Photoreceptors; 3.3.3 A Variety of Putative Pore Selectivity Filter Sequences Have Evolved; 3.4 Properties and Organization of TRP Channels; 3.4.1 General Structural Features of TRP Channels; 3.4.2 Structural Features of Drosophila TRP and TRPL Channels 3.4.3 Organization in Supramolecular Signaling Complex via Scaffold Protein INAD3.4.4 Assembly of TRP Channels; 3.4.5 Biophysical Properties of TRP Channels; 3.4.6 Stimulus-Dependent TRP Channel Translocation; 3.4.7 TRP Channel Regulation by Phosphorylation; 3.5 Gating Mechanism of Drosophila TRP Channels; 3.5.1 Lipids Activate Light-Sensitive Channels in the Dark; 3.5.2 PUFA as Second Messenger of Excitation; 3.5.3 Is Drosophila TRP a Mechanosensitive Channel?; 3.6 Concluding Remarks; Acknowledgments; References; Chapter 4: Sensory Mechanotransduction and Thermotransduction in Invertebrates 4.1 Structure and Function of TRP Channels in Invertebrates4.2 Mechanosensation and Thermosensation in Adult Caenorhabditis Elegans; 4.2.1 Response to Gentle (and Harsh Touch) in C. Elegans Adults, TRPN; 4.2.2 Response to Harsh Touch in C. Elegans Adults, TRPV and TRPA; 4.2.3 Response to Harsh Touch and Low Temperatures in C. Elegans Adults, TRPV and TRPA; 4.2.4 Response to Harsh Touch and High Temperatures in C. Elegans Adults, TRPV; 4.3 Mechanosensation in Adult and Larval Drosophila Flies; 4.3.1 Mechanosensory Neurons in Drosophila Adult Flies, TRPN and TRPV
• Publisher Details: Boca Raton, FL : CRC Press
• Publication Date: 2017
• Extent: 1 online resource
• Subjects: 572.6; SCIENCE / Life Sciences / Biology / Molecular Biology; SCIENCE / Life Sciences / Neuroscience; Cell Biology; Molecular Biology; Neuroscience; TRP channels; Membrane proteins; Ion channels; Neurobiology; Biochemistry; SCIENCE / Life Sciences / Biochemistry; Electronic books
• Languages: English
• ISBNs: 9781315152837; 1315152835; 9781351648868; 1351648861
• Related ISBNs: 9781498755245; 1498755240
• Access Rights: Legal Deposit; Only available on premises controlled by the deposit library and to one user at any one time; The Legal Deposit Libraries (Non-Print Works) Regulations (UK).
• Access Usage: Restricted: Printing from this resource is governed by The Legal Deposit Libraries (Non-Print Works) Regulations (UK) and UK copyright law currently in force.