Biomarkers of environmentally associated disease : technologies, concepts, and perspectives /: technologies, concepts, and perspectives. (©2002)

• Record Type: Book
• Further Information: Note: [edited by] Samuel H. Wilson, William A. Suk.
• Other Names: Wilson, Samuel H, 1939-; Suk, William A (William Alfred)
• Contents: Front Cover; Editors; Contributors; Contents; 1. Overview and future of molecular biomarkers of exposure and early disease in environmental health; 2. Ethical and legal considerations in biological markers research; 3. Scientific and policy issues affecting the future of environmental health sciences; 4. Ecogenetics: genetic susceptibility to environmental adversity; 5. Toxicogenomics and pharmacogenomics: basic principles, potential applications, and issues; 6. Individual susceptibility to exposures: a role for genetic variation in DNA repair genes. 7. Studies of DNA repair and human cancer: an update8. DNA adducts as biomarkers of DNA damage in lung cancer; 9. Tamoxifen-DNA adducts: biomarkers for drug-induced endometrial cancer; 10. Polycyclic aromatic hydrocarbon DNA adducts and human cancer; 11. Quantitative PCR: a sensitive biomarker of gene-specific DNA damage and repair; 12. Fidelity of DNA synthesis as a molecular biomarker; 13. Mutational specificity of environmental carcinogens. 14. Learning-induced modulation of neural cell adhesion molecule polysialylation state as a biomarker of prior inorganic lead exposure during the early postnatal period15. Molecular biomarkers for mercury; 16. Validity of mercury exposure biomarkers; 17. Urinary arsenic species in relation to drinking water, toenail arsenic concentrations and genetic polymorphisms in GSTM1 in New Hampshire; 18. Molecular responses of mammalian cells to nickel and chromate exposure; 19. Chromium: exposure, toxicity, and biomonitoring approaches. 20. Using plankton food web variables as indicators for the accumulation of toxic metals in fish21. Validation of exposure and risk biomarkers: aflatoxin as a case study; 22. Biomarkers of early effect in the study of cancer risk; 23. Proteomics in toxicology: an experience with gentamicin; 24. Xenopus laevis genomic biomarkers for environmental toxicology studies; 25. Molecular biomarkers targeting signal transduction systems: the AH receptor pathway; 26. Measuring oxidative damage caused by environmental stressors: potential for reversal and abatement. 27. Biomarkers of male reproductive health28. Peripheral benzodiazepine receptors: molecular biomarkers of neurotoxicity; 29. Biomarkers of organ injury from chemical exposure: concurrent inflammation as a determinant of susceptibility; 30. Modulation of GAP junctional communication by "epigenetic" toxicants: a shared mechanism in teratogenesis, carcinogenesis, atherogenesis, immunomodulation, reproductive- and neurotoxicities; 31. Exposure to POPs and other congeners; 32. Polybrominated diphenyl ethers: route, dose, and kinetics of exposure to humans.
• Publisher Details: Boca Raton : Lewis Publishers
• Publication Date: 2002
• Copyright Date: 2002
• Extent: 1 online resource (582 pages), illustrations
• Subjects: 616.9/8; Environmentally induced diseases -- Diagnosis; Environmentally induced diseases -- Molecular aspects; Biochemical markers; Tumor markers; Biomarkers; Environmental Exposure -- analysis; Molecular Biology -- methods; Salud ambiental; Maladies de l'environnement -- Diagnostic; Maladies de l'environnement -- Aspect moléculaire; Marqueurs biologiques; Marqueurs tumoraux; MEDICAL -- Infectious Diseases; HEALTH & FITNESS -- Diseases -- Contagious; Electronic books
• Languages: English
• ISBNs: 9781420032208; 1420032208
• Related ISBNs: 1566705967; 9781566705967
• Notes: Note: Includes bibliographical references and index.; Note: Print version record.
• Access Rights: Legal Deposit; Only available on premises controlled by the deposit library and to one user at any one time; The Legal Deposit Libraries (Non-Print Works) Regulations (UK).
• Access Usage: Restricted: Printing from this resource is governed by The Legal Deposit Libraries (Non-Print Works) Regulations (UK) and UK copyright law currently in force.