Carcinogenic and anticarcinogenic food components. (2006)

• Record Type: Book
• Further Information: Note: Edited by Wanda Baer-Dubowski, Agnieszka Bartoszek, Danuta Malejka-Giganti.
• Other Names: Baer-Dubowska, Wanda; Bartoszek, Agnieszka; Malejka-Giganti, Danuta
• Contents: Front cover; Preface; The Editors; Contributors; Contents; 1; Food and Cancer: Development of an Association; 1.1 Historical Background; 1.2 Nutritional Needs; 1.3 Carcinogenic Potential of Food; 1.4 Anticarcinogenic Activity of Food; 1.5 Genetically Determined Variability of Cancer Risk; 1.6 Epidemiologic Evidence for an Association between Nutrition and Cancer; 1.7 Final Remarks; References; 2; Molecular Mechanisms of Carcinogenesis; 2.1 Introduction; 2.2 Multistage Process of Carcinogenesis; 2.2.1 Molecular Mechanisms of Mutagenesis and Carcinogenesis; 2.2.1.1 Role of DNA Damage. 2.2.1.2 Protooncogenes and Tumor Suppressor Genes: Regulators of Cell Growth2.2.2 Molecular and Cellular Events during Initiation and Promotion of Carcinogenesis; 2.2.2.1 Activation of Oncogenes; 2.2.2.2 Inactivation of Tumor Suppressor Genes; 2.2.2.3 Alteration of Genes Regulating Apoptosis; 2.2.3 Molecular and Cellular Events during Progression of Carcinogenesis; 2.3 Dietary Initiators and Promoters of Carcinogenesis in Humans; 2.3.1 Examples of Dietary Initiators; 2.3.2 Examples of Dietary Promoters; 2.4 Endogenous DNA Damage; 2.5 Concluding Remarks; References; 3. Metabolism of Chemical Carcinogens3.1 Introduction; 3.2 Enzymatic Systems Involved in Metabolism of Carcinogens; 3.2.1 Cytochromes P450; 3.2.2 Other Carcinogen-Metabolizing Enzymes; 3.2.2.1 UDP-Glucuronosyl Transferases (UDPGT; EC 2.4.1.17); 3.2.2.2 Sulfotransferases (SULT; EC 2.8.2); 3.2.2.3 Glutathione S-Transferases (GST; EC 2.5.1.18); 3.2.2.4 N-acetyltransferases (NAT; EC 2.3.1.5); 3.2.2.5 Microsomal Epoxide Hydrolase (mEH; EC 3.3.2.3); 3.2.3 The Role of Enzymes of the Intestinal Microflora in Bioactivation of Foodborne Carcinogens; 3.2.4 Concluding Remarks. 3.3 Metabolic Pathways of Selected Foodborne Carcinogens3.3.1 Polycyclic Aromatic Hydrocarbons (PAHs); 3.3.2 Aflatoxin B1 (AFB1); 3.3.3 Heterocyclic Aromatic Amines (HAAs); 3.3.4 N-nitrosamines; 3.4 Concluding Remarks; References; 4; Genotoxic Food Components; 4.1 Introduction; 4.2 Genotoxicity in Risk Assessment of Diet-Related Carcinogenic Factors; 4.3 Genotoxic Food Components; 4.3.1 Mycotoxins; 4.3.2 N-Nitroso Compounds; 4.3.3 Polycyclic Aromatic Hydrocarbons; 4.3.4 Heterocyclic Aromatic Amines; 4.3.5 Acrylamide; 4.3.6 Miscellaneous Foodborne Genotoxic Agents. 4.4 Products of Oxidative Processes4.4.1 Reactive Oxygen Species with DNA-Damaging Potential; 4.4.2 Genotoxic Products of Lipid Peroxidation; 4.5 Conclusions; References; 5; Impact of Food Preservation, Processing, and Cooking on Cancer Risk; 5.1 Introduction; 5.2 Preservation and Processing; 5.2.1 Salted Foods; 5.2.2 Nitrates (V)/(III) and N-Nitroso Compounds (NOCs); 5.2.3 Smoked Foods -- Polycyclic Aromatic Hydrocarbons (PAHs); 5.3 Cooking Methods; 5.3.1 Heterocyclic Aromatic Amines (HAAs); 5.3.2 Polycyclic Aromatic Hydrocarbons (PAHs); 5.3.3 Acrylamide; 5.4 Conclusions; References; 6.
• Publisher Details: Boca Raton, FL : Taylor & Francis
• Publication Date: 2006
• Extent: 1 online resource (393 pages), illustrations
• Subjects: 616.99/4071; Carcinogens; Food -- Toxicology; Functional foods; Cancer -- Diet therapy; Cancer -- Diet therapy; Carcinogens; Food -- Toxicology; Functional foods; MEDICAL -- Oncology; HEALTH & FITNESS -- Diseases -- Cancer; Cancer -- Diet therapy; Carcinogens; Food -- Toxicology; Functional foods; Anticarcinogenic Agents; Electronic books
• Languages: English
• ISBNs: 1420039261; 9781420039269; 9780849320965; 0849320968
• Related ISBNs: 0849320968
• Notes: Note: Includes bibliographical references and index.; Note: Print version record.
• Access Rights: Legal Deposit; Only available on premises controlled by the deposit library and to one user at any one time; The Legal Deposit Libraries (Non-Print Works) Regulations (UK).
• Access Usage: Restricted: Printing from this resource is governed by The Legal Deposit Libraries (Non-Print Works) Regulations (UK) and UK copyright law currently in force.