Delivery strategies for antisense oligonucleotide therapeutics. (2018)

• Record Type: Book
• Further Information: Note: Edited by Saghir Akhtar.
• Editors: Akhtar, Saghir
• Contents: Ch. 1. Disrupting the flow of genetic information with antisense oligodeoxynucleotides: Research and Therapeutic Applications / D. Kregenow, M.Z. Ratajeczak and A. Gewirtz -- Ch. 2. Cellular Delivery of Ribozymes / D.A. Elkins and J.J. Rossi -- Ch. 3. Improved structural design and cellular uptake of triplex-forming oligonucleotides / N. Chaudhary, J.S. Bishop, K. Jayaraman and J.K. Guy-Caffey -- Ch. 4. Pharmacokinetics and delivery of oligonucleotides to the brain / L. Neckers, D.A. Geselowitz and C. Chavany -- Ch. 5. In vivo pharmacokinetics of oligonucleotides following administration by different routes / V.V. Vlassov, L.A. Yakubov, V. Karamyshev, L. Pautova, E. Rykova and M. Nechaeva -- Ch. 6. Nuclease-resistant DNA therapeutics / E. Wickstrom -- Ch. 7. Self-stabilized oligonucleotides as novel antisense agents / S. Agrawal, J. Temsamani and J. Tang -- Ch. 8. Circular oligonucleotides as potential modulators of gene expression / E.T. Kool.
• Publisher Details: Roca Raton : CRC Press, Taylor & Francis Group
• Publication Date: 2018
• Copyright Date: 1995
• Extent: 1 online resource (305 pages), illustrations
• Subjects: 615.3/1; Antisense nucleic acids -- Therapeutic use; Oligonucleotides -- Therapeutic use; Drugs -- Dosage forms; Drug Design & Development; Pharmacology; Biopharmaceutics; MEDICAL / Pharmacology; Electronic books
• Languages: English
• ISBNs: 9781315150901; 1315150905; 9781351366137; 1351366130
• Related ISBNs: 9781138558571; 9781138505896
• Notes: Note: Includes bibliographical references and index.; Note: Online resource; title from PDF title page (EBSCO, viewed August 24, 2017).
• Access Rights: Legal Deposit; Only available on premises controlled by the deposit library and to one user at any one time; The Legal Deposit Libraries (Non-Print Works) Regulations (UK).
• Access Usage: Restricted: Printing from this resource is governed by The Legal Deposit Libraries (Non-Print Works) Regulations (UK) and UK copyright law currently in force.