Process chemistry in the pharmaceutical industry. Challenges in an ever changing climate / Volume 2, (©2008)

• Record Type: Book
• Other Titles: Challenges in an ever changing climate
• Further Information: Note: Edited by Kumar Gadamasetti, Tamim Braish.
• Other Names: Gadamasetti, Kumar G, 1949-; Braish, Tamim
• Contents: Process Chemistry in the Pharmaceutical Industry: Challenges in an Ever-Changing Climate—An Overview; K. Gadamasetti ; Emerging Trends in Process Chemistry; T.F. Braish, F. De Knaep, and K. Gadamasetti ; Varenicline: Discovery Synthesis and Process Chemistry Developments; J.W. Coe, H.A. Watson Jr., and R.A. Singer ; The SUTENT® Story; R. Vaidyanathan ; An Efficient and Scalable Process for the Preparation of a Potent MC4 Receptor Agonist; C. Savarin, J. Chung, J.A. Murry, R.J. Cvetovich, C. McWilliams, D. Hughes, J. Amato, G. Boice, K. Conrad, E. Corley, R. Reamer, and L. DiMichele ; Process Research and Development of LY414197, a 5HT2B Antagonist; A. Borghese and A. Merschaert ; To Overcome the Hurdles: Coping with the Synthesis of Robalzotan, a Complex Chroman Antidepressant; H. J.Federsel and A. Sveno ; Chiral Amine Synthesis—Strategies, Examples, and Limitations; T.C. Nugent ; Unnatural Amino Acids; D.J. Ager ; The Chemical Development of a Potential Manufacturing Route to the Endothelin Antagonists UK-350, 926 and UK-349, 862; C.P. Ashcroft, S. Challenger, A.M. Derrick, Y. Hajikarimian, and N.M. Thomson ; Cefovecin Sodium: A Single-Dose Long-Acting Antibiotic for Use in Companion Animals; T. Norris ; The Lithium–Halogen Exchange Reaction in Process Chemistry; W.F. Bailey and T.L. Rathman ; Oxetan-3-one: Chemistry and Synthesis; G. Wuitschik, E.M. Carreira, M. Rogers-Evans, and K. Müller ; Well-Defined (NHC)Pd (II) Complexes and Their Use in C–C and C–N Bond-Forming Reactions; O. Navarro and S.P. Nolan ; Toward Truly Efficient Organic Reactions in Water; C. Ogawa and S. Kobayashi ; The Chemical Development of the Commercial Route to Sildenafil Citrate; P.J. Dunn ; Stereoselective Enzymatic Synthesis of Intermediates Used for Antihypertensive, Antiinfective, and Anticancer Compounds; R.L. Hanson ; Designing Robust Crystallization Processes for Active Pharmaceutical Ingredients—From Art to Science; D. Wieckhusen ; In Situ Mid-Infrared Spectroscopy for Process Development; D.A. Conlon, W. Izzo, J. Christopher McWilliams, R.A. Reamer, F. Xu, and P. Collins ; Optimizing an Asymmetric Homologation in a Tandem Asymmetric Homologation–Homoaldol Reaction; J.C. McWilliams and R.A. Reamer ; Development of Efficient One-Pot Process in the Synthesis of Sitagliptin: Application of Online-Infrared for Kinetic Studies to Probe the Reaction Mechanism; F. Xu ; Mid-Infrared Monitoring Applications during Development of the Vinyl Ether Formation Step in the Preparation of Aprepitant (Emend® ); D.A. Conlon, W. Izzo, and P. Collins ; Process Analytical Technology in the Manufacture of Bulk Active Pharmaceuticals—Promise, Practice, and Challenges; C.A. Mojica and L. St. Pierre-Berry ; PEGylation of Biological Macromolecules; J.J. Buckley, R.F. Finn, J. Mo, L.A. Bass, and S.V. Ho ; Microwave Technology in Process Optimization; F. Mavandadi ; Process Development Considerations for Therapeutic Monoclonal Antibodies in Mammalian Cell Culture; S. Casnocha, R. Fedechko, P. Mensah, J. Mott, and S. Nema ; Reaction Progress Kinetic Analysis: A Powerful Methodology for Streamlining Pharmaceutical Reaction Steps; N. Zotova, S.P. Mathew, H. Iwamura, and D.G. Blackmond ; Trends in Outsourcing; J. Lu and I. Shinkai ; Sourcing Pharmaceutical Products in China and India; D. Robins and S. Hannon Index
• Publisher Details: Boca Raton : CRC Press
• Publication Date: 2008
• Copyright Date: 2008
• Extent: 1 online resource (xxviii, 480 pages), illustrations (some color)
• Subjects: 615/.19; Pharmaceutical chemistry; Chemical processes; Chemistry, Pharmaceutical -- methods; Drug Evaluation; Pharmaceutical Preparations -- analysis; Research Design; Technology, Pharmaceutical -- methods; MEDICAL -- Drug Guides; MEDICAL -- Pharmacology; MEDICAL -- Pharmacy; MEDICAL -- Nursing -- Pharmacology; Chemical processes; Pharmaceutical chemistry; Electronic books
• Languages: English
• ISBNs: 9781420008357; 1420008358; 9781628705515; 1628705515
• Related ISBNs: 0849390516; 9780849390517
• Notes: Note: Includes bibliographical references.
• Access Rights: Legal Deposit; Only available on premises controlled by the deposit library and to one user at any one time; The Legal Deposit Libraries (Non-Print Works) Regulations (UK).
• Access Usage: Restricted: Printing from this resource is governed by The Legal Deposit Libraries (Non-Print Works) Regulations (UK) and UK copyright law currently in force.