Synthetic nucleic acids as inhibitors of gene expression : mechanisms, applications, and therapeutics implications /: mechanisms, applications, and therapeutics implications. (©2005)

• Record Type: Book
• Further Information: Note: Edited by Levon Michael Khachigian.
• Other Names: Khachigian, Levon
• Contents: Therapeutic application of ribozymes for cardiovascular disease -- Development of ribozymes as cancer therapeutics -- RNA interference: a technology based on an ancient gene silencing pathway -- RNA-cleaving DNA enzymes in gene silencing: room for improvement? -- Deoxyribozymes and medical innovation -- Effect of modifications on the intracellular activity of a DNA enzyme -- Potential therapeutic applications of DNA enzymes and siRNAs against viral and cellular genes -- Use of DNAzymes for target gene validation -- DNAzymes targeting immediate-early genes as inhibitors of angiogenesis and restenosis -- Decoy oligodeoxynucleotides as viable pharmaceutical drugs.
• Publisher Details: Boca Raton : CRC Press
• Publication Date: 2005
• Copyright Date: 2005
• Extent: 1 online resource (182 pages), illustrations (some color)
• Subjects: 572.8; Catalytic RNA; Repressors, Genetic; Genetic regulation; SCIENCE -- Life Sciences -- Molecular Biology; BIOGRAPHY & AUTOBIOGRAPHY -- Science & Technology; Catalytic RNA; Genetic regulation; Repressors, Genetic; Nucleic Acids -- physiology; Nucleic Acids -- therapeutic use; DNA, Catalytic; Gene Silencing -- drug effects; RNA, Catalytic; Electronic books
• Languages: English
• ISBNs: 1420037897; 9781420037890
• Related ISBNs: 0849330254; 9780849330254
• Notes: Note: Includes bibliographical references and index.; Note: Print version record.
• Access Rights: Legal Deposit; Only available on premises controlled by the deposit library and to one user at any one time; The Legal Deposit Libraries (Non-Print Works) Regulations (UK).
• Access Usage: Restricted: Printing from this resource is governed by The Legal Deposit Libraries (Non-Print Works) Regulations (UK) and UK copyright law currently in force.