Protein misfolding in neurodegenerative diseases : mechanisms and therapeutic strategies /: mechanisms and therapeutic strategies. (©2008)

• Record Type: Book
• Further Information: Note: Edited by H. John Smith, Claire Simons, Robert D.E. Sewell.
• Other Names: Smith, H. J, 1930-; Simons, Claire; Sewell, Robert D. E
• Contents: Protein folding and misfolding, relevance to disease, and biological function / Massimo Stefani -- Alzheimer's disease / Charlotte E. Teunissen and Tischa J.M. van der Cammen -- Improving cholinergic transmission -- Cholinergic transmission and acetylcholine release enhancers / Pierre Francotte, Pascal de Tullio, and Bernard Pirotte -- AChE and its inhibition / Jure Stojan -- AChE inhibitors and their clinical assessment / Pierre Francotte, Pascal de Tullio, and Bernard Pirotte -- Reduction in plaque formation -- Secretase and APP processing / Christian Czech, Helmut Jacobsen, and Celine Adessi -- Mechanism of plaque formation and A[B] aggregation inhibitors / Christian Czech, Helmut Jacobsen, and Celine Adessi -- Nonsteroidal anti-inflammatory drugs / Bruno P. Imbimbo and Francesca Speroni -- 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors / Dario Cattaneo -- A[B] polymerization reduction / Harry LeVine III and Corrine E. Augelli-Szafran -- Carbonic anhydrase activators as potential anti-Alzheimer's disease agents / Claudiu T. Supuran and Andrea Scozzafava -- Detection and reduction of neurofibrillary lesions / Jeff Kuret -- Protein misfolding in Alzheimer disease : pathogenic or protective? / Rudy J. Castellani [and others] -- Enhancement of brain retinoic acid levels / Ann B. Goodman [and others] -- Parkinson's disease : what is it? what causes it? and how can it be cured? / Tom Foltynie, Andrew W. Michell, and Roger A. Barker -- Restoring dopamine levels / P. Nuno Palma . [and others] -- Huntington's disease / Claire-Anne Gutekunst and Fran Norflus -- Amyotrophic lateral sclerosis (motor neuron disease) / Teresa Sanelli [and others] -- Transmissible spongiform encephalopathies / Michael D. Geschwind and Giuseppe Legname -- Overview / H. John Smith, Robert D.E. Sewell, and Claire Simons.
• Publisher Details: Boca Raton, FL : CRC Press
• Publication Date: 2008
• Copyright Date: 2008
• Extent: 1 online resource (xxiv, 565 pages), illustrations (some color)
• Subjects: 616.8/0471; Nervous system -- Degeneration -- Etiology; Nervous system -- Degeneration -- Treatment; Nervous system -- Degeneration -- Pathophysiology; Protein folding; Neurodegenerative Diseases -- etiology; Protein Folding; Neurodegenerative Diseases -- physiopathology; Neurodegenerative Diseases -- therapy; HEALTH & FITNESS -- Diseases -- Nervous System (incl. Brain); MEDICAL -- Neurology; Electronic books
• Languages: English
• ISBNs: 9781420007145; 1420007149
• Related ISBNs: 9780849373107; 0849373107
• Notes: Note: Includes bibliographical references and index.; Note: Print version record.
• Access Rights: Legal Deposit; Only available on premises controlled by the deposit library and to one user at any one time; The Legal Deposit Libraries (Non-Print Works) Regulations (UK).
• Access Usage: Restricted: Printing from this resource is governed by The Legal Deposit Libraries (Non-Print Works) Regulations (UK) and UK copyright law currently in force.