Reactive oxygen metabolites : chemistry and medical consequences /: chemistry and medical consequences. (©2001)

• Record Type: Book
• Further Information: Note: Manfred K. Eberhardt.
• Other Names: Eberhardt, Manfred K
• Contents: THE PROS AND CONS OF LIVING IN AN OXYGEN ATMOSPHERE; BASIC CHEMISTRY OF RADICALS; Definition and History; Formation of Radicals; Reactions of Radicals; CHEMISTRY OF OXYGEN-DERIVED RADICALS; Historical Perspective; Definitions; One-Electron Reduction of Oxygen; Superoxide Radical Anion; Peroxyl Radicals; Hydroxyl Radical; CHEMISTRY OF ELECTRONICALLY EXCITED STATES; Singlet Oxygen; Excited Carbonyl Compounds; FORMATION OF REACTIVE OXYGEN METABOLITES IN VIVO; Introduction; Mitochondrial Electron Transport; Hemoproteins; Flavin-Linked Oxidases; The Microsomal Enzymme System; Phagocytosis; Electronically Excited Carbonyl; Compounds via Enzymatic Oxidations; Endothelium-Derived Relaxing Factor (EDRF); REACTIONS OF REACTIVE OXYGEN METABOLITES WITH IMPORTANT BIOMOLECULES; General Remarks about Oxygen Radical Investigations; Reactions of Hydroxyl Radicals with Fatty Acids; Mechanism of Lipid Peroxidation-Induced Pathogenesis; Chemistry of Oxygen Radical Damage to DNA; DNA Damage via Electronically Excited States; Biological Markers for in vivo Oxidative Damage; NITRIC OXIDE; Chemical Formation of Nitric Oxide; Chemistry of Nitric Oxide; Important Reactions in the Deactivation of Nitric Oxide; Reactions of Nitrogen Dioxide; Nitric Oxide and Superoxide Dismutase; The Chemical Nature of EDRF; Chemistry of Peroxynitrite-Peroxynitrous Acid; The Role of Peroxzynitrite-Peroxynitrous Acid in vivo; Protective Effect of Nitric Oxide in Oxygen Radical Induced Damage; Toxicity of Nitric Oxide via Release of Fe(II) from Ferritin; Protein Derived Radicals and Nitric Oxide; ANTIOXIDANTS; Introduction; Superoxide Dismutases; Reactions of Oxygen and Oxygen Radicals with Ascorbic Acid; Uric Acid; Melatonin; Vitamin E; Antioxidan and Prooxidant Activity of Flavonoids; Carotenoids; Proteins which form Complexes with Transition-Metal Ions; Peptides as Antioxidants; Do Antioxidants Prevent Diseases in vivo?; PATHOLOGICAL PROCESSES INVOLVING REACTIVE OXYGEN METABOLITES; Introduction; Aging and Cancer; Inflammation, Cell Division, and Cancer; Neurodegenerative Disorders; Lung Diseases; Atherosclerosis; Ischemia-Reperfusion; Oxidative Stress and Lifestyle; CONCLUSION; REFERENCES
• Publisher Details: Boca Raton : CRC Press
• Publication Date: 2001
• Copyright Date: 2001
• Extent: 1 online resource (591 pages), illustrations
• Subjects: 612/.01524; Active oxygen in the body; Active oxygen; Free radicals (Chemistry) -- Pathophysiology; Reactive Oxygen Species -- metabolism; Disease -- etiology; Free Radicals -- chemistry; MEDICAL -- Biochemistry; Active oxygen; Active oxygen in the body; Free radicals (Chemistry) -- Pathophysiology; Electronic books
• Languages: English
• ISBNs: 9781420041521; 1420041525; 0849308917; 9780849308918
• Notes: Note: Includes bibliographical references (399-527) and indexes.; Note: Print version record.
• Access Rights: Legal Deposit; Only available on premises controlled by the deposit library and to one user at any one time; The Legal Deposit Libraries (Non-Print Works) Regulations (UK).
• Access Usage: Restricted: Printing from this resource is governed by The Legal Deposit Libraries (Non-Print Works) Regulations (UK) and UK copyright law currently in force.