Preclinical drug development. (2005)

• Record Type: Book
• Further Information: Note: [edited by] Mark C. Rogge, David R. Taft.
• Other Names: Rogge, Mark C; Taft, David R
• Contents: The Scope of Preclinical Drug Development: An Introduction and Framework. Interspecies Differences in Physiology and Pharmacology: Extrapolating Preclinical Data to Human Populations. Transgenic Animals for Preclinical Drug Development. Pharmacokinetics/ADME of Small Molecules. Pharmacokinetics/ADME of Large Molecules. Preclinical Pharmacokinetic-Pharmacodynamic Modeling and Simulation. Formulation and Route of Administration - Influencing Drug. Assessment of Pharmacokinetics and Drug Activity: Isolated Organ. Alternate Methods for Assessing Absorption, Metabolism and Routes of Toxicity Evaluations: ICH Guidelines and Current Practice. Application of Pathology in Safety Assessment. Principles of Toxicogenomics: Implications for Preclinical Drug Development. Utilizing the Preclinical Database to Support Clinical Drug Development
• Publisher Details: Boca Raton : Taylor & Francis
• Publication Date: 2005
• Extent: 1 online resource (xiv, 575 pages, [8] pages of plates), illustrations
• Subjects: 615/.19; Drug development; Drug Evaluation, Preclinical -- methods; Drug Industry -- methods; Drug evaluation, Preclinical -- Methods; Drug industry -- Methods; Médicaments -- Développement; MEDICAL -- Drug Guides; MEDICAL -- Pharmacology; MEDICAL -- Pharmacy; MEDICAL -- Nursing -- Pharmacology; Drug development; Electronic books
• Languages: English
• ISBNs: 0849360234; 9780849360237; 9781574448825
• Related ISBNs: 157444882X; 157444882X
• Notes: Note: Includes bibliographical references and index.; Note: Print version record.
• Access Rights: Legal Deposit; Only available on premises controlled by the deposit library and to one user at any one time; The Legal Deposit Libraries (Non-Print Works) Regulations (UK).
• Access Usage: Restricted: Printing from this resource is governed by The Legal Deposit Libraries (Non-Print Works) Regulations (UK) and UK copyright law currently in force.