In silico technologies in drug target identification and validation. (©2006)

• Record Type: Book
• Further Information: Note: Edited by Darryl León, Scott Markel.
• Other Names: León, Darryl; Markel, Scott
• Contents: Pattern matching / Scott Markel and Vinodh N. Rajapakse -- Tools for computational protein annotation and function assignment / Jaume M. Canaves -- The impact of genetic variation on drug discovery and development / Michael R. Barnes -- Mining of gene expression data / Aedin Culhane and Alvis Brazma -- Text mining / Bruce Gomes, William Hayes, and Raf Podowski -- Pathways and networks / Eric Minch and Ivayla Vatcheva -- Molecular interactions: learning from protein complexes / Ana Rojas, David de Juan, and Alfonso Valencia -- In silico siRNA design / Darryl León -- Predicting protein subcellular localization using intelligent systems / Rajesh Nair and Burkhard Rost -- Three-dimensional structures in target discovery and validation / Seán I. O'Donoghue, Robert B. Russell, and Andrea Schafferhans -- Comparative genomics / Viviane Siino, Bruce Pascal, and Christopher Sears -- Pharmacogenomics / Bahram Ghaffarzadeh Kermani -- Target identification and validation using human simulation models / Seth Michelson, Didier Scherrer, and Alex L. Bangs -- Using protein targets for in silico structure-based drug discovery / Tad Hurst -- Database management / Arek Kasprzyk and Damian Smedley -- BioIT hardware configuration / Philip Miller -- BioIT architecture: software architecture for bioinformatics research / Michael Dickson -- Workflows and data pipelines / Michael Peeler -- Ontologies / Robin A. McEntire and Robert Stevens.
• Publisher Details: Boca Raton : CRC/Taylor & Francis
• Publication Date: 2006
• Copyright Date: 2006
• Extent: 1 online resource (490 pages, [4] pages of plates), illustrations (some color)
• Subjects: 615/.19; Drug development; Drug development -- Computer simulation; Drug Delivery Systems -- methods; Chemistry, Pharmaceutical; Computational Biology; MEDICAL -- Drug Guides; MEDICAL -- Pharmacology; MEDICAL -- Pharmacy; MEDICAL -- Nursing -- Pharmacology; Electronic books
• Languages: English
• ISBNs: 9781420015737; 1420015737
• Related ISBNs: 1574444786; 9781574444780
• Notes: Note: Includes bibliographical references and index.; Note: Print version record.
• Access Rights: Legal Deposit; Only available on premises controlled by the deposit library and to one user at any one time; The Legal Deposit Libraries (Non-Print Works) Regulations (UK).
• Access Usage: Restricted: Printing from this resource is governed by The Legal Deposit Libraries (Non-Print Works) Regulations (UK) and UK copyright law currently in force.